FACT: Vitamins, such as vitamin D, are needed to reduce hair loss
FACT: Chemotheraphy reduces vitamin D
OBSERVATION: Vitamin D reduces hair loss due to chemotherapy: reasons include:
- Vitamin D can reduce the amount of chemo needed, so less hair killed off
- Less chemo results in less reduction in Vitamin D
- Vitamin D can keep the hair healthy.
Google search "hair loss" chemotherapy "vitamin d" 3,80,000 hits Dec 2011
Great hair regrowth June 2012: Henry Lahore, admin of VitaminDWiki
My having a high level of vitamin D for over 2 years helped reduce many aches and pains, but did not stop or even slow my hair loss (age 66)
Even taking all of the bone/vitamin D cofactors did not stop hair loss (Magnesium, Silicon, Boron, etc)
However, 2 months ago I decided to add scalp massage, which had really helped my father re-populate his scalp
(he was a carpenter who worked outdoors most of his life, probably getting plenty of vitamin D)
Nightly 3 minute scalp massage (to increase blood circulation) resulted in detectable hair re-growth in 2 weeks and excellent regrowth in 6 weeks.
I leave the scalp massager plugged in next to the bed so that it takes no time to setup for the nightly massage.
Observation: Vitamin D3 + cofactors + massage has worked extremely well for me.
Perhaps just massage would have helped, I do not know.
Conclusion for others: None: I have no idea if the combination will work for you.
There are a huge number of scalp massagers sold on Amazon - both mechanical and electric
I happened to purchase an electric massager made by Wahl for $22, which has a hair attachment (not shown)
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Feb 2010 Meta-analysis of Vitamin D and Hair Loss
Clipped from above on chemotherapy-induced hair loss
"...Limited studies have been done in humans to elaborate the role of vitamin D in the hair cycle. A potential application for vitamin D is in chemotherapy-induced hair loss. Topical calcitriol has been shown to protect against chemotherapy-induced alopecia caused by paclitaxel and cyclophosphamide. However, topical calcitriol failed to protect against chemotherapy-induced hair loss caused by a combination of 5-fluorouracil, doxorubicin, and cyclophosphamide and a combination of cyclophosphamide, methotrexate, and 5-fluorouracil 36, 37.”
The Hair Cycle and Vitamin D Receptor - 2011
Archives of Biochemistry and Biophysics, doi:10.1016/j.abb.2011.10.002; Available online 7 October 2011.
Marie B. Demay ,
Endocrine Unit, Massachusetts General Hospital and Harvard Medical School, 50 Blossom St, Thier 11, Boston, MA 02114
The Vitamin D receptor (VDR) plays a critical role in epidermal homeostasis. The ligand-dependent actions of the VDR attenuate epidermal keratinocyte proliferation and promote keratinocyte differentiation. Calcium can compensate for the absence of the VDR in maintaining a normal program of epidermal keratinocyte differentiation both in vitro and in vivo. In contrast, the effects of VDR ablation on the hair follicle cannot be prevented by maintaining normal calcium levels and are independent of 1,25-dihydroxyvitamin D. These actions of the VDR are critical in the keratinocyte stem cell population that resides in the bulge region of the hair follicle. Absence of a functional VDR leads to a self-renewal and lineage progression defect in this population of stem cells, resulting in the absence of post-morphogenic hair cycles. The molecular partners and downstream target genes of the VDR in this unique population of cells have not yet been identified.
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Does D matter? The role of vitamin D in hair disorders and hair follicle cycling. - 2010
Dermatol Online J. 2010 Feb 15;16(2):3.
Amor KT, Rashid RM, Mirmirani P.
Department of Dermatology, University of Texas and MD Anderson Cancer Center, Houston, Texas, USA. rashidrashid.mdphd at yahoo.com
BACKGROUND: The role of vitamin D in the proliferation and differentiation of keratinocytes is well known within the field of dermatology.
OBJECTIVE: We sought to evaluate the role that vitamin D and the vitamin D receptor play in the hair cycle and assess how this can be clinically applied to the treatment of hair disorders.
METHODS: A MEDLINE search (1955-July 2009) was preformed to find relevant articles pertaining to vitamin D, the vitamin D receptor, and hair loss.
RESULTS: The vitamin D receptor, independent of vitamin D, plays an important role in hair cycling, specifically anagen initiation.
The role of vitamin D in hair follicle cycling is not as well understood.
LIMITATIONS: The review is broad and there are limited human studies available to date.
CONCLUSION: Additional studies to evaluate the role of vitamin D in the hair cycle should be done.
Treatments that up regulate the vitamin D receptor may be successful in treating hair disorders and are a potential area of further study.
PMID: 20178699 CLICK HERE for full text in VitaminDWiki
Note: the only reference the paper has for Vitamin D and baldness had 3 groups of men, all having about 35 ng of vitamin D
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- Natural News June 2010 Vitamins
- Prevent Hair Loss: Vitamin A, B, C, D, and Vitamin E
- Vitamin D reduces hair loss by stimulating the hair follicle and the cells that form the hair shaft.
- D is one of many many vitamins needed to prevent hair loss date unknown
Skin Pharmacol Physiol. 2013;26(2):101-7. doi: 10.1159/000346698. Epub 2013 Feb 20.
Rasheed H1, Mahgoub D, Hegazy R, El-Komy M, Abdel Hay R, Hamid MA, Hamdy E.
1Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Evaluation of serum ferritin and vitamin D levels in females with chronic telogen effluvium (TE) or female pattern hair loss (FPHL), in order to validate their role in these common hair loss diseases.
Eighty females (18 to 45 years old) with hair loss, in the form of TE or FPHL, and 40 age-matched females with no hair loss were included in the study. Diagnosis was based upon clinical examination as well as trichogram and dermoscopy. Serum ferritin and vitamin D2 levels were determined for each participant.
Serum ferritin levels in the TE (14.7 ± 22.1 μg/l) and FPHL (23.9 ± 38.5 μg/l) candidates were significantly lower than in controls (43.5 ± 20.4 μg/l). Serum vitamin D2 levels in females with
- TE (28.8 ± 10.5 nmol/l) and
- FPHL (29.1 ± 8.5 nmol/l) were significantly lower than in
- controls (118.2 ± 68.1 nmol/l; p < 0.001).
These levels decreased with increased disease severity.
Serum ferritin cut-off values for TE and FPHL were 27.5 and 29.4 μg/l, respectively, and those for vitamin D were 40.9 and 67.9 nmol/l.
Low serum ferritin and vitamin D2 are associated with hair loss in females with TE and FPHL. Screening to establish these levels in cases of hair loss and supplementing with them when they are deficient may be beneficial in the treatment of disease.
Female pattern hair loss VitD: 13.5 ng vs controls(no FP hair loss): 17.2 ng -2016
Serum Vitamin D3 Level in Patients with Female Pattern Hair Loss.
Int J Trichology. 2016 Jul-Sep;8(3):116-20. doi: 10.4103/0974-7753.188965.
Banihashemi M1, Nahidi Y1, Meibodi NT2, Jarahi L3, Dolatkhah M4.
1Department of Dermatology, Cutaneous Leishmaniasis Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2Department of Pathology, Cutaneous Leishmaniasis Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3Addiction Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4Department of Ophthalmology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Female pattern hair loss (FPHL) is the most common cause of alopecia in women, characterized by diffuse nonscarring hair loss in frontal, central, and parietal areas of the scalp. Pathophysiology of FPHL is still not well known, and it is probably a multifactorial genetic trait. FPHL is also observed in women without increased androgen levels, which raises the likelihood of androgen-independent mechanisms and explains the lack of response to antiandrogen treatments in some patients. Vitamin D is a factor that has recently been considered in dealing with these patients. The purpose of this study was to evaluate the serum levels of Vitamin D in patients with FPHL and compare it with healthy controls.
In this case-control study, 45 women with FPHL were evaluated as well as the same number of healthy women matched for age, hours spent under sunlight per day, and body mass index. Serum 25(OH) D3 level was measured using ELISA.
60% of FPHL patients were in 15-30 years old age group with the mean standard deviation (SD) age of 29.11 (7.30) years. In the majority of patients (66.7%), severity of hair loss was Ludwig I. Mean (SD) serum Vitamin D3 level in patient and control group was 13.45 (8.40) and 17.16 (8.96), respectively. T-test showed a significant difference between the two groups in terms of Vitamin D3 serum levels (P = 0.04).
This study indicated the correlation between the incidence of FPHL and decreased serum levels of Vitamin D3. It is recommended to evaluate serum Vitamin D3 levels as well as other hormone assays in these patients.
PMID: 27625563 DOI: 10.4103/0974-7753.188965
Download the PDF from VitaminDWiki
See also VitaminDWiki
- Hair loss strongly associated with poor vitamin D receptors– Dec 2016
- 90 percent of people with Spot Baldness (Alopecia Areata) had low level of vitamin D – March 2014
- Relationship Between Nutritional Habits and Hair Calcium Levels in Young Women March 2011
- Diffuse hair loss - 2009.pdf not just getting older
- Vitamin D2 patent granted to prevent hair loss during chemotherapy – 2002
- We suspect the vitamin D3 would work as well, if not better than D2
- A patent for a vitamin D treatment of a health problem is always a good indication that it probably works
- Redhead – Red hair - vitamin D
- Red hair apparently allows more production of vitamin D from the same amount of sunlight
- Hypothesis: Stem cells need vitamin D too – Jan 2012
- Stem Cell Transplants consume vitamin D – July 2011
- Vitamin D and Hair disorders – Feb 2010
- Vitamin D Shows Promise in Curing Baldness – July 2012
See also web
- Vitamin D and Hair Loss (Alopecia): New Research Confirms Link Jan 2012, discussses
mutated Vitamin D receptors and hair loss in mice - California study
study in Texas
another mouse and VDR study from Mass General
California study with nude mice and VDR
- Vitamin D deficiency causing more women to seek hair transplants in the Gulf May 2013
Women in the Middle East have such low levels of vitamin D that some are losing their hair.
Only 3% of the people going to hair clinics in Europe are women, but 20% are women in the Middle East
CLICK HERE for vitamin D deficiency in the Middle East
- What Is the Connection Between Vitamin D and Hair Loss?
Research using hairless mice shows that vitamin D protects against hair loss caused by chemotherapy administered during cancer treatment, but the results have not been replicated in humans.
- 7 Reasons Women Lose Their Hair — And 7 Fixes
1 reason is low vitamin D - only 1 sentence: Huffingpost July 2015
- Vitamin D deficiency in alopecia areata 2014
Vitamin D deficiency: 91% in those with AA, 33% in controls
- Reduced level of 25-hydroxyvitamin D in chronic/relapsing Alopecia Areata April 2013
Download the PDF from VitaminDWiki
- Vitamind3Blog - Does Vitamin D Deficiency Cause Hair Loss? Feb 2011 with interesting comments
- Vitamind3Blog - Update Jan 2012 with some of the items below
- Vitamin D3 analogs stimulate hair growth in nude mice 2002 PDF on-line
- Sydney Morning Herald Feb 2010
Hormone in pill and vitamin D blamed for women's hair loss
- Does D matter? The role of vitamin D in hair disorders and hair follicle cycling - Feb 2010 full text of peer-reviewed publication is on-line
MEDLINE review (1955-July 2009) RESULTS: The vitamin D receptor, independent of vitamin D, plays an important role in hair cycling, specifically anagen initiation. The role of vitamin D in hair follicle cycling is not as well understood.
- Exposed: Symptoms Of Vitamin D Deficiency In Ladies... Aug 2011
- Vitamin D and Male Pattern Hair Loss: Is There a Link? Aug 2016
Article decides - probably there is a link
See also web - graying hair is related to several vitamin D deficient diseases
- This Is Why You Have Gray Hair Mercola, March 2016
Obesity, Thyroid disorders, anemia and vitiligo
"people with premature graying but no other identifiable risk factor were 4.4 times as likely to have osteopenia"
My beard growth perhaps aided by Vitamin D and Zinc
Started growing my beard at age 70 (2016)
Facial hair and head hair growing well
Vitamin D and cofactors - which include Zinc
Google Search for Beard and Vitamin D ==> 200,000 web pages
Google Search for Beard and Zinc ==> 400,000 web pages
Short url = http://is.gd/HairVitD