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Overview Suntans melanoma and vitamin D

Consensus on the following:

  • UV radiation at the ground consists mainly of UVA, some UVB, and a tiny amount of UVC
  • Sun, sunbeds/tanning beds/some sun bulbs contain both UVA and UVB radiation
  • UVA (315 -400 nm) radiation induces pigment tanning within seconds of UVA and light exposure
    • UVA tanning fades within 2 hours and does not increase melanin in skin
  • UVB (280-315 nm) radiation
    • induces vitamin D synthesis
    • delayed tanning (increases melanin in skin after several days)
    • is mainly responsible for sunburn (erythema), photoaging, photoimmunosuppression
  • Windows (glass) block UVB radiation
  • Modern sunscreens block UVB and UVA, but some of them block UVA poorly or are photo-unstable in this region
  • There has been an increase in melanoma incidence in recent years
  • Tanning beds produce higher levels of UVA radiation than the sun - even at the equator
  • UVB radiation, but not UVA radiation, induces melanoma in genetically modified animals
    • The newest epidemiological evidence suggest that UVA as well as UVB is associated with human melanoma
  • Epidemiological studies published over the last years demonstrated the association between sunbed use and melanoma.
  • Many countries restrict the amount of UVB (vitamin D) from tanning beds (due to mouse study)
  • UVB decreases faster than UVA when far from equator or winter season

Confusion/Disagreement

Sunburn (Erythema), cataracts, and development of skin cancer are related mostly to UVB radiation.
Ban all people under age 18 from using tanning beds
Increase alcohol consumption is strongly associated with increased melanoma (see bottom of page)

See also VitaminDWiki

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Death from melanoma (without ulcers) greatly decreased if have lots of vitamin D receptors – May 2014 has the following chart
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See also VitaminDWiki UVA and Melanoma

See also web

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Clipped from SkinCheck org Where does Melanoma occur

  • Anywhere, including places never exposed to the sun.
  • In Caucasian males, the most common location is the trunk (especially the back).
  • In Caucasian females, the most common locations are the legs (especially the back of lower legs) and trunk.
  • Among Asians, Hispanics, and African-Americans, the most common locations are the feet and hands.
    Skin is lighter (less melatonin), so more UVB can damage the feet and hands

From: Vitamin D from Sunbeds

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From: Sunbed survey in Ireland

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From: UV creates Vitamin D

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GrassrootsHealth Melanoma & sunscreen associated in 7 studies (PDF and video)

from PDF and video available at http://www.grassrootshealth.net/

Melanoma and suncreens Time line -2010

Chart from http://www.detertec.com/sun_radiometry.html

Red = sunlight (probably on ground); other lines = amount of light filtered thru different sunscreens
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Current sunscreen controversies: a critical review.

Photodermatol Photoimmunol Photomed. 2011 Apr;27(2):58-67. doi: 10.1111/j.1600-0781.2011.00557.x.
Burnett ME, Wang SQ., Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

Background/purpose: Sunscreens are believed to be a valuable tool in providing photoprotection against the detrimental effects of UV radiation, a known carcinogen. However, a number of controversies have developed regarding their safety and efficacy. This review summarizes the relevant studies surrounding these controversies.

Methods: Evidence of the prevention of skin cancer, an oft-cited reason for sunscreen use, was examined as it pertains to squamous cell carcinoma, basal cell carcinoma and melanoma. We also reviewed studies examining the effects of sunscreen on the synthesis of vitamin D, an essential nutrient whose role in health and disease continues to grow. Lastly, we analyzed studies surrounding the safety and toxicity of oxybenzone, retinyl palmitate and nanoparticles of zinc oxide (ZnO) and titanium dioxide (TiO(2) ).

Results: The overwhelming majority of available data is drawn from studies conducted using antiquated sunscreen formulations.
Nonetheless, our research revealed that topical use of sunscreen protects against squamous cell carcinoma, does not cause vitamin D deficiency/insufficiency in practice and has not been demonstrated to adversely affect the health of humans.

Conclusion: Given the established benefits of UV protection, the use of sunscreens remains an important part of an overall photoprotective strategy. Future sunscreens with improved formulation should ideally offer superior protection. With increased usage of sunscreen by the public, continuous and vigilant monitoring of the overall safety of future products is also needed.
© 2011 John Wiley & Sons A/S. PMID: 21392107


Germany also considers that adding vitamin D might reduce melanoma

Serum 25-hydroxyvitamin D serum levels in a large German cohort of melanoma patients.
Br J Dermatol. 2012 Aug 9. doi: 10.1111/j.1365-2133.2012.11212.x.
Gambichler T, Bindsteiner M, Höxtermann S, Kreuter A.
Department of Dermatology, Ruhr-University Bochum, Bochum, Germany.

Background:? Observational studies have suggested that 25-hydroxyvitamin D (25OHD) is associated with better outcomes in patients with malignant melanoma (MM).

Objectives:? To study the relationship between serum 25OHD levels and clinical parameters in a large German cohort of MM patients.

Methods:? We prospectively investigated the 25OHD serum levels of 764 MM patients using the direct competitive chemiluminescence LIAISON® immunoassay.
MM patients taking 25OHD supplements were not included.

Results:? Median serum 25OHD baseline levels were 12.3 ng/ml (lower quartile: 7.3 ng/ml, upper quartile: 20.2 ng/ml). 564 (764/73.8%) patients had 25OHD deficiency (25OHD < 20 ng/ml), 188 (764/18.8%) had 25OHD insufficiency (25OHD ? 20 < 30 ng/ml), and only 55 (764/7.2%) patients had serum 25OHD levels within the normal range (? 30 ng/ml). Using a multiple regression model, lower 25OHD levels were significantly associated with higher Breslow tumour thickness (class: < 1 mm; ? 1 - 4 mm; > 4 mm: regression coefficient -1.45, P = 0.028) and higher AJCC 2002 melanoma stage (regression coefficient: -0.79, P = 0.036).

Conclusions:? In MM patients, decreased 25OHD serum levels are associated with increased tumour thickness and advanced tumour stage.
Hence, evidence is accumulating that patients with MM might benefit from 25OHD supplements.

Copyright © 2012 British Association of Dermatologists. PMID: 22880705


Some Chinese are really wanting to get whiter skin or avoid Skin Cancer/Wrinkles

Meet the 'Face-Kini', the latest craze to hit China's beaches as bathers wear masks to beat the sun's harmful raysDailyMail UK Aug 2012 - which have photos like the following
Ski mask on beach in China - 2012.jpg


Sunshine: Dangerous or Healthy? 2009

  • Comment in a NYT interview of Dr. Bernard Ackerman, Demratoligist, who has authored 600 papers
    "the field is just replete with nonsense." For example, Dr. Ackerman does not believe that the link between melanoma and sun exposure (a central dogma of dermatology) has been proven.
    He is deeply tanned and is not afraid to expose his body to the sun. Dr. Ackerman does, however, recommend that folks avoid excessive skin exposure to avoid premature aging of the skin.
    He also does not believe that sunburn, even the kind that causes blistering of the skin, necessarily leads to cancer later in life.
    Basically, according to Dr. Ackerman, "the research is inconsistent and fails to make the case."

Alcohol and Melanoma: More Proof that this Deadly Skin Cancer is not caused by Sunlight

Sunlight Institute, Nov 2013

  • 1993 study: women who drank two or more drinks per day had an increased risk of melanoma of 250%.
  • Oct 2013 study
    (1) 7+ drinks per week had a 64% increased risk of melanoma;
    (2) higher lifetime alcohol consumption was positively correlated to risk of the disease;
    (3) higher current alcohol consumption similarly correlated to a higher risk:
    (4) current alcohol intake also predicted higher risk;
    (5) a preference for white wine or liquor also predicted increased risk.
  • Sunlight Instutiute refutes the claim that melanoma is caused by sunlight

If already have had skin cancer, a form of Vitamin B3 lowers the rate of future ones by 23% - RCT May 2015

Overview Suntans melanoma and vitamin D        

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Attached files

ID Name Comment Uploaded Size Downloads
6417 UV sunscren P&G.jpg admin 23 Feb, 2016 21:48 42.38 Kb 1261
3566 Skin cancer and pigmentation.pdf PDF - 2014 admin 23 Jan, 2014 13:02 110.92 Kb 1207
485 UVB and UVB vs height of the sun lie on ground - from creates 2009.gif Editor 07 Mar, 2011 15:10 10.55 Kb 10356
484 UVB and UVB vs height of the sun - from creates 2009.gif Editor 07 Mar, 2011 15:10 14.51 Kb 16684
483 survey of sunbed parlors in Ireland.gif Editor 07 Mar, 2011 15:09 35.92 Kb 4684
482 sunbed vs sun spectrum - from UV creates - 2009.gif Editor 07 Mar, 2011 15:09 16.08 Kb 4984
481 Spectrum of all sources - from vitamin D from sunbeds.gif Editor 07 Mar, 2011 15:09 22.70 Kb 5657
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