Resveratrol Role in Autoimmune Disease-A Mini-Review.
Nutrients. 2017 Dec 1;9(12). pii: E1306. doi: 10.3390/nu9121306.
Oliveira ALB1, Monteiro VVS2, Navegantes-Lima KC3, Reis JF4, Gomes RS5, Rodrigues DVS6, Gaspar SLF7, Monteiro MC8.
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Autoimmune

IBD

Psoriasis

RA

LUPUS

Autoimmune diseases are still considered to be pressing concerns due the fact that they are leaders in death and disability causes worldwide. Resveratrol is a polyphenol derived from a variety of foods and beverages, including red grapes and red wine. Anti-inflammatory, antioxidant, and antiaging properties of resveratrol have been reported, and in some animal and human studies this compound reduced and ameliorated the progression of autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and type 1 diabetes mellitus. Thus, this review aims to summarize and critically analyze the role of resveratrol in the modulation of several organ-specific or systemic autoimmune diseases.