Vitamin D Receptor activation should reduce ARDS associated with COVID-19

Created August 2020

Vitamin D receptor stimulation to reduce acute respiratory distress syndrome (ARDS) in patients with coronavirus SARS-CoV-2 infections

J J Steroid Biochem Mol Biol. 2020 Sep; 202: 105719.11. doi: 10.1016/j.jsbmb.2020.105719

ose Manuel Quesada-Gomez,a,b Marta Entrenas-Castillo,c and Roger Bouillond,*

Items in both categories Vitamin D Receptor and Virus are listed here: {category} * Omega-3, Magnesium, Zinc, Quercetin, non-daily Vit D, Curcumin, intense exercise, Ginger, Essential oils, etc** Note: The founder of VitaminDWiki uses 10 of the 12 known VDR activators 1. Vitamin D Receptor category has the following {include}

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Coronavirus infection is a serious health problem awaiting an effective vaccine and/or antiviral treatment. The major complication of coronavirus disease 2019 (COVID-19), the Acute Respiratory Distress syndrome (ARDS), is due to a variety of mechanisms including cytokine storm, dysregulation of the renin-angiotensin system, neutrophil activation and increased (micro)coagulation. Based on many preclinical studies and observational data in humans, ARDS may be aggravated by vitamin D deficiency and tapered down by activation of the vitamin D receptor. Several randomized clinical trials using either oral vitamin D or oral Calcifediol (25OHD) are ongoing. Based on a pilot study, oral calcifediol may be the most promising approach. These studies are expected to provide guidelines within a few months.

Tags: Resveratrol Virus Vit D Receptor