Lupus associated with both low vitamin D and Vitamin D receptor problems

Created October 2016

Vitamin D and Systemic Lupus Erythematosus: Myth or Reality?

Isr Med Assoc J. 2016 Mar-Apr;18(3-4):177-82.

Watad A, Neumann SG, Soriano A, Amital H, Shoenfeld Y.

* Lupus **category listing has items along with related searches** * If Lupus in family – 5 times more likely to get Lupus if low vitamin D and poor CYP24A1 – June 2016 * CYP24A1 is not the VDR, but another gene which is also invisible to Vitamin D tests * Lupus reduced with vitamin D intervention – Feb 2014 Items in both categories Lupus and Vitamin D Receptor are listed here: {category} --- 1. Vitamin D Receptor has the following {include}

📄 Download the PDF from VitaminDWiki

 

image

There is growing interest in the contribution of vitamin D deficiency to autoimmunity. Several studies have shown an association between low levels of vitamin D and autoimmune disorders, including multiple sclerosis, rheumatoid arthritis, type 1 diabetes, autoimmune thyroid diseases, celiac disease, and systemic lupus erythematosus (SLE). Vitamin D receptor ligands can mediate immunosuppressive effects. It has been suggested that low levels of this hormone contribute to the immune activation in lupus and other autoimmune diseases. This review updates and summarizes the literature on the association between vitamin D and SLE, and discusses the various correlations between vitamin D and SLE activity, clinical expressions, serology, and gene polymorphisms of vitamin D receptors.

PMID: 27228639

Tags: Lupus Vit D Receptor