Chronic Kidney Disease Patients need Vitamin K

Vitamin K in Chronic Kidney Disease.

Nutrients. 2019 Jan 14;11(1). pii: E168. doi: 10.3390/nu11010168.

Cozzolino M1, Mangano M2, Galassi A3, Ciceri P4, Messa P5, Nigwekar S6.

Poor kidneys rarely get enough or the right form of vitamin D – Feb 2019 1. # Items in both categories Kidney and Vitamin K are listed here: {category} 1. Kidney category starts with {include} 1. Overview Vitamin K and Vitamin D contains the following summary {include}

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Vitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme γ-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kidney disease (CKD) patients suffer from subclinical vitamin K deficiency, suggesting that this represents a population at risk for the biological consequences of poor vitamin K status. This deficiency might be caused by exhaustion of vitamin K due to its high requirements by vitamin K-dependent proteins to inhibit calcification.