Vitamin D: Is It the Best Thing Under the Sun - Medscape

Created February 2013

Robert Finn; Deborah Flapan; Darbe Rotach

The following is the first of 25 images

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The number of research studies on vitamin D has soared in recent years.

Citations of studies involving vitamin D increased from 1142 in the year 2000 to 3877 in 2012.

In comparison, citations for research on vitamin A and vitamin C have remained more or less level.

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References

  1. Ryan LM, Teach SJ, Singer SA, et al. Bone mineral density and vitamin D status among African American children with forearm fractures. Pediatrics. 2012;30:e553-560. doi: 10.1542/peds.2012-0134. Epub 2012 Aug 27 Abstract

  2. Sonneville KR, Gordon CM, Kocher MS, et al. Vitamin D, calcium, and dairy intakes and stress fractures among female adolescents. Arch Pediatr Adolesc Med. 2012;166:595-600. doi:10.1001/archpediatrics.2012.5. Abstract

  3. Bischoff-Ferrari HA, Willett WC, Orav EJ, et al. A pooled analysis of vitamin D dose requirements for fracture prevention. N Engl J Med. 2012367:40-49. Abstract

  4. Camargo CA Jr, Ganmaa D, Frazier AL, et al. Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics. 2012;130:e561-567. Abstract

  5. Bergman P, Norlin AC, Hansen S, et al. Vitamin D3 supplementation in patients with frequent respiratory tract infections: a randomised and double-blind intervention study. BMJ Open. 201213;2:e001663. Abstract

  6. Murdoch DR, Slow S, Chambers ST, et al. Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. JAMA. 2012;308:1333-1339. Abstract

  7. Greer RM, Portelli SL, Hung BS, et al. Serum vitamin D levels are lower in Australian children and adolescents with type 1 diabetes than in children without diabetes. Pediatr Diabetes. 2013;14:31-41. Abstract

  8. Gorham ED, Garland CF, Burgi AA, et al. Lower prediagnostic serum 25-hydroxyvitamin D concentration is associated with higher risk of insulin-requiring diabetes: a nested case-control study. Diabetologia. 2012;55:3224-3227. Full text

  9. Brøndum-Jacobsen P, Benn M, Jensen GB, et al. 25-hydroxyvitamin D levels and risk of ischemic heart disease, myocardial infarction, and early death: population-based study and meta-analyses of 18 and 17 studies. Arterioscler Thromb Vasc Biol. 2012;32:2794-2804. Abstract

  10. Wang L, Song Y, Manson JE, et al. Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease. A meta-analysis of prospective studies. Circ Cardiovasc Qual Outcomes. 2012;5:819-829. Abstract

  11. Wood AD, Secombes KR, Thies F, et al. Vitamin D3 supplementation has no effect on conventional cardiovascular risk factors: a parallel-group, double-blind, placebo-controlled RCT. J Clin Endocrinol Metab. 2012;97:3557-3568. Abstract

  12. Crozier SR, Harvey NC, Inskip HM, et al. Maternal vitamin D status in pregnancy is associated with adiposity in the offspring: findings from the Southampton Women's Survey. Am J Clin Nutr. 2012;96:57-63. Abstract

  13. Turer CB, Lin H, Flores G. Prevalence of vitamin D deficiency among overweight and obese US children. Pediatrics. 2013;131:e152-61. Abstract

  14. LeBlanc ES, Rizzo JH, Pedula KL, et al. Associations between 25-hydroxyvitamin D and weight gain in elderly women. J Womens Health (Larchmt). 2012;21:1066-1073. Abstract

  15. Grant WB, Cannell JJ. Autism prevalence in the United States with respect to solar UV-B doses: an ecological study. Dermato-Endocrinology. 2013;5:1-6. Full Text

  16. Balion C, Griffith LE, Strifler L, et al. Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology. 2012;79:1397-1405. Abstract

  17. Mizwicki MT, Menegaz D, Zhang J, et al. Genomic and nongenomic signaling induced by 1a,25(OH)2-vitamin D3 promotes the recovery of amyloid-β phagocytosis by Alzheimer's disease macrophages. J Alzheimers Dis. 2012;29:51-62. Abstract

  18. Whitehouse AJ, Holt BJ, Serralha M, et al. Maternal serum vitamin D levels during pregnancy and offspring neurocognitive development. Pediatrics. 2012;129:485-493. Abstract

  19. Kojima G, Bell C, Abbott RD, et al. Low dietary vitamin D predicts 34-year incident stroke: the Honolulu Heart Program. Stroke. 2012;43:2163-2167. Abstract

  20. Décard BF, von Ahsen N, Grunwald T, et al. Low vitamin D and elevated immunoreactivity against Epstein-Barr virus before first clinical manifestation of multiple sclerosis. J Neurol Neurosurg Psychiatry. 2012;83:1170-1173. Abstract

  21. Rastelli AL, Taylor ME, Gao F, et al. Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial. Breast Cancer Res Treat. 2011;129:107-116. Abstract

  22. Lasco A, Catalano A, Benvenga S. Improvement of primary dysmenorrhea caused by a single oral dose of vitamin D: results of a randomized, double-blind, placebo-controlled study. Arch Intern Med. 2012;172:366-367. Full Text

  23. Glover TL, Goodin BR, Horgas AL, et al. Vitamin D, race, and experimental pain sensitivity in older adults with knee osteoarthritis. Arthritis Rheum. 2012;64:3926-3935. Abstract

  24. Coussens AK, Wilkinson RJ, Hanifa Y, et al. Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment. Proc Natl Acad Sci U S A. 2012;109:15449-15454. Abstract

  25. Wu AC, Tantisira K, Li L, et al. Effect of vitamin D and inhaled corticosteroid treatment on lung function in children. Am J Respir Crit Care Med. 2012;186:508-513. Abstract

  26. Lehouck A, Mathieu C, Carremans C, et al. High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med. 2012;156:105-114. Full Text

  27. Ananthakrishnan AN, Khalili H, Higuchi LM, et al. Higher predicted vitamin D status is associated with reduced risk of Crohn's disease. Gastroenterology. 2012;142:482-489. Abstract

  28. Khalili H, Huang ES, Ananthakrishnan AN, et al. Geographical variation and incidence of inflammatory bowel disease among US women. Gut. 2012;61:1686-1692. Abstract

  29. Bhan I, Burnett-Bowie SA, Ye J, et al. Clinical measures identify vitamin D deficiency in dialysis. Clin J Am Soc Nephrol. 2010;5:460-467. Abstract

  30. Alvarez JA, Law J, Coakley KE, et al. High-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: a pilot, randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2012;96:672-679. Abstract

  31. Hujoel PP. Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis. Nutr Rev. 2013;71:88-97. Abstract

  32. Kjærgaard M, Waterloo K, Wang CE, et al. Effect of vitamin D supplement on depression scores in people with low levels of serum 25-hydroxyvitamin D: nested case-control study and randomised clinical trial. Br J Psychiatry. 2012;201:360-368. Abstract

  33. Leow L, Simpson T, Cursons R, et al. Vitamin D, innate immunity and outcomes in community acquired pneumonia. Respirology. 2011;16:611-616. Abstract

  34. Rejnmark L, Avenell A, Masud T, et al. Vitamin D with calcium reduces mortality: patient level pooled analysis of 70,528 patients from eight major vitamin D trials. J Clin Endocrinol Metab. 2012;97:2670-2681. Abstract

  35. Noordam R, de Craen AJ, Pedram P, et al. Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study. CMAJ. 2012;184:E963-968. Full Text

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