The earlier the better- preconception vitamin D
The earlier the better: preconception vitamin D and protection against pregnancy loss.
Lancet Diabetes Endocrinol. 2018 Jun 5. pii: S2213-8587(18)30178-5. doi: 10.1016/S2213-8587(18)30178-5. [Epub ahead of print]
Hewison M, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, Centre for Endocrinology, Diabetes and Metabolism, U. of Birmingham and Birmingham Health Partners, Birmingham, B15 2TT, UK m.hewison@bham.ac.uk.
PDF is available free at Sci-Hub
PMID: 29884467 DOI: 10.1016/S2213-8587(18)30178-5
This is an editorial comments on
Mumford SL, Garbose RA, Kim K, et al.
Association of preconception serum 25-hydroxyvitamin D concentrations with livebirth and pregnancy loss: a prospective cohort study. Lancet Diabetes Endocrinol 2018; online May 30. In VitaminDWiki Preconception vitamin D is great - every extra 10 ng associated with 10 percent more likely to have live birth – Aug 2018
Preconception supplementation appears to reduce problems with
Becoming pregnant
Miscarriage
First trimester supplementation reduces problems with
Infant teeth
Autism
Healthy pregnancies need lots of vitamin D has the following summary
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Fertility and Sperm category contains the following summary
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Fertility
Having a good level of vitamin D before conception helps – Aug 2018
Birth rates doubled with Vitamin D - 300,000 IU for infertile men – RCT Nov 2017
Poor fertility in both women and men associated with low vitamin D – review Feb 2018
Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
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See also
Ensure a healthy pregnancy and baby - take Vitamin D before conception
Some related publications by M Hewison
Vitamin D, the placenta and early pregnancy: effects on trophoblast function Feb 2018 PDF online
Dysregulation of maternal and placental vitamin D metabolism in preeclampsia Feb 2017 PDF online
Search VitaminDWiki for HEWISON 905 items as of Aug 2018
Decidua immunity and Vitamin D – dissertation July 2018 Hewison was thesis advisor