Preemies still have low vitamin D at age 6

Created October 2019

Evaluation of vitamin D3 levels and morphotic parameters of blood in prematurely born children at six years of age.

Sci Rep. 2019 Oct 21;9(1):15089. doi: 10.1038/s41598-019-51613-y.

* Preterm babies have low vitamin D, but recover in 6 weeks with 800 IU supplementation – Jan 2019 * Premature infants (30 weeks) who got 800-1000 IU of vitamin D were much healthier – March 2017 * Expect that the premies in Poland did not get Vitamin D supplementation * Preterm birth rate increased 60 percent in 50 years (US) * Now 12% in US vs 6% in Poland - perhaps due to more women (black) with low levels of VItamin D --- 1. Infant-Child category has items and starts with {include} {include}

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Walicka-Cupryś K1,2, Zajkiewicz K3,4, Drzał-Grabiec J3,4, Perenc L3,4.

  • 1 Medical Faculty, Institute of Physiotherapy, University of Rzeszow, Rejtana 16c, Rzeszów, 35-959, Poland. kwcuprys@univ.rzeszow.pl.

  • 2 Centre for Innovative Research in Medical and Natural Sciences, Medical Faculty, University of Rzeszow, Warzywna 1a, Rzeszów, 35-310, Poland. kwcuprys@univ.rzeszow.pl.

  • 3 Medical Faculty, Institute of Physiotherapy, University of Rzeszow, Rejtana 16c, Rzeszów, 35-959, Poland.

  • 4 Centre for Innovative Research in Medical and Natural Sciences, Medical Faculty, University of Rzeszow, Warzywna 1a, Rzeszów, 35-310, Poland.

In Poland the preterm children, with the birth rate reaching 6.3%, constitute a serious medical problem. The system of specialistic clinics provides them with the multidisciplinary care for the first 3 years of life, including the monitoring of hematologic parameters in relation with anemia and osteopenia. The aim of this study was to assess the vitamin D3 level and morphotic parameters of blood in children who were prematurely born at the time when they are about to start school. The study was carried out in a group of 92 children, aged 6 years ±0.63, including 54 preterm children born at gestational age <32 weeks - and 38 full-term children. A basic anthropometric measures and assessment of morphotic parameters and the vitamin D3 level were assessed. Statistical analyses were carried out using Shapiro-Wilk W-test, Student's t-test and Mann-Whitney U test.

Preterm children had significantly lower the vitamin D3 level than controls.

This also refers to some morphotic parameters of blood, such as

  • level of hemoglobin,

  • mean corpuscular hemoglobin concentration and platelets.

Prematurely born 6-7 year-old children have significantly lower vitamin D3 levels in blood serum than normal and significantly lower hemoglobin levels than full-term children.

Tags: Deficiency Infant-Child