Osteoporosis treated by Vitamin D + Vitamin K2 + Vitamin B + Zinc + Mg + Silica etc (no surprise)
The Use of Vitamin D, Zinc, Magnesium, Silicon, Copper, Methylsulfonylmethane (MSM), Vitamin K and B-Complex in Patients with Osteoporosis: A Nutritional and Pathophysiological Rationale
Ann of Rehabil & Regene Med 2026
Antonio Spinarelli1*’ Giovanna Porcelli1, Florianna Palmiotto1, Pierangela Nardella1, Giovanni Allegretti2, Nicola Giorgio2, & Vito Conserva2 Italy
Osteoporosis is a chronic skeletal disorder characterized by reduced bone mass and structural deterioration of bone tissue, leading to increased fragility and risk of fractures. Nutritional factors play a pivotal role in bone health, particularly in aging populations. This article explores the synergistic effects of essential micronutrients—vitamin D, zinc, magnesium, silicon, copper, and methylsulfonylmethane (MSM)—along with vitamin K and B-complex vitamins, in the prevention and management of osteoporosis. We examine their physiological functions, mechanisms of action on bone remodeling, and the evidence from clinical and experimental studies. Our findings suggest that these nutrients, especially when used in combination, may improve bone mineral density (BMD), reduce inflammation, enhance collagen formation, and mitigate fracture risk. Integrating nutritional strategies into conventional treatment may offer a more holistic approach to bone health in osteoporotic patients.
Related in VitaminDWiki
- Expert consensus: Osteoporosis needs Vitamin D
- Osteoporosis 60% more likely if low Magnesium intake
- Vitamin K helps vitamin D build bone
- Vitamin D Cofactors in a nutshell
- Silicon, Vitamin D and Bone Health - multiple studies
- Healthy bones need Ca, Silicon, Vitamins B, C, D, and K
- Vitamin D Receptor activators (Resveratrol, Curcumin ,Quercetin) all improve bone – Review
Increasing activation of VDR increases bone growth (not mentioned in the study) - Silicon or silica as a vitamin D co-factor Note: A similar supplements +VDR activators have been used by the founder of VitaminDWiki for over a decade to repair cracks in his teeth