Hospice and palliative care – Vitamin D, CBD, and Medical Cannabis

• Vitamin D, CBD, and Medical M all relieve pain

• Vitamin D, CBD may also cure

  • Vitamin D, CBD are legal in all 50 US states
• Medical Cannabis is one of the following (unclear as of 2017)
  • CBD
  • THC + CBD
  • THC

Vitamin D

• Vitamin D supplementation to palliative cancer patients: protocol of a double-blind, randomised controlled trial ‘Palliative-D RCT 2020
  • 4,000 IU/day of Vitamin D
• Vitamin D supplementation to palliative cancer patients shows positive effects on pain and infections—Results from a matched case-control study Aug 2017
  • 4,000 IU/day of Vitamin D
  • 
  • 📄 Download the PDF from VitaminDWiki

CBD

• CBD benefits - review of literature April 2019

• Use of cannabinoids in cancer care: palliative care March 2016

  • 📄 Download the PDF from VitaminDWiki
• Investigation of Cannabis for Chronic Pain and Palliative Care RCT due 2022
  • Compare smoking high vs no CBD 3 times a week

• Cancer: Cannabinoids and CBD Research Overview Feb 2017 Good Overview

• Cannabidiol (CBD) Links to recent research

• Study: Cannabidiol (CBD) May Prevent Degenerative Disc Disease 2015?

• THE ENDOCANNABINOID SYSTEM

  • "Extensive preclinical research—much of it sponsored by the U.S. government—indicates that CBD has potent anti-tumoral, antioxidant, anti-spasmodic, anti-psychotic, anti-convulsive, and neuroprotective properties. CBD directly activates serotonin receptors, causing an anti-anxiety effect, as well."
• International Cannaboid Research Society
  • 28th annual conference in 2018
  • They publish the Journal Cannabis and Cannabinoid Research Example titles - with free PDFs
  • Willingness to Participate in Longitudinal Research Among People with Chronic Pain Who Take Medical Cannabis: A Cross-Sectional Survey
  • Translating Endocannabinoid Biology into Clinical Practice: Cannabidiol for Stroke Prevention
  • Cannabis Roots: A Traditional Therapy with Future Potential for Treating Inflammation and Pain
  • Cannabis as a Substitute for Opioid-Based Pain Medication: Patient Self-Report
  • Cannabis and Pain: A Clinical Review
• Consumer Labs Feb 2018
  • Cost of 10 mg of CBD ranged from 80 cents to $4.54 Excelent material and review of products - behind a subscription paywall
• Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs July 2018
  • Randomized Controlled Trial - owners reported a lot of improvment in 1 month, vets not so much. 4 mg per kg of body weight
  • 📄 Download the PDF from VitaminDWiki

Medical cannabis

• What ethical considerations should be taken into account when prescribing medical cannabis to terminally ill patients? Can professionals justify such prescriptions?

• Medical marijuana in hospice and palliative care Hospice and Palliative care blog – 2015?

• Medicinal cannabis in palliative care; update from trial leader Nov 2016

• CBD available topically, orally, and as spray - similar to Vitamin D Feb 2018

• Functional Forum: Medical Cannabis: The What, Why and How of a New and Ancient Medicine. - Nov 2017

  • Notes by founder of VitaminDWiki

THC + CBD has been approved for MS in Europe

CBD is in finaly stages of being approved by FDA for Epilepsy

Endocannabinoid system in very old - at least 500 million years

All vertebrates have Endocannaboid systems

Cannaboids are found in breast milk

Omega -3 is a Cannaboid precursor

CB1 receptor in the brain and many other tissues

CB1 is the most abundant "g-coupled" receptor in the mammalian brain

CB2 receptors in immune system and many other tissues

Black pepper activates CB2 receptor

UCLA researcher is focusing on reduction of Pain with Cannaboids -

Recent NIH report found that Cannaboid are associated with essentially all human diseases

CBD is especially important for all auto-immune diseases (note: Diabetes is now #3 killer in the US and #1 in Mexico)

CBD greatly reduced auto-immune problems after bone marrow transplant

CBD prescribed to 26,000 chronic pain patients in Israel

Turpins in marijuana might help CBD cross the blood-brain barrier

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See also VitaminDWiki

• Pain not relieved by monthly 100,000 IU of vitamin D (need 50,000 IU weekly) – RCT Feb 2018

• Quality of Life

• Chronic Pain reported 38 percent less often if supplemented with Vitamin D – meta-analysis Sept 2016

• Off topic – CBD conflict – W.H.O. non addicting, may have medical benefits, DEA US class 1 narcotic – Dec 2017

• Palliative cancer benefit of 4,000 IU of Vitamin D – less opioids, infection, and CRP – Aug 2017

• Chemotherapy and vitamin D - many studies

• Off topic: Cannabis and disease studies at GreenMedInfo – Dec 2015

VitaminDWiki - Pain - chronic category contains

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VitaminDWiki pages with CBD in title (7 as of Aug 2022)

This list is automatically updated

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