Depression treated by 50K IU Vitamin D weekly (but not 1,000 IU daily) – meta-analysis

Efficacy of vitamin D in the treatment of depression: a systematic review and meta-analysis

Actas Esp Psiquiatr . 2021 Jan;49(1):12-23. Epub 2021 Jan 1.

Ana Lázaro Tomé 1, M José Reig Cebriá 2, Aurora González-Teruel 3, Juan Antonio Carbonell-Asíns 4, Carlos Cañete Nicolás 5, Miguel Hernández-Viadel 5

Trials using infrequent high doses did much better

📄 Download the PDF from VitaminDWiki

Vitamin D is a fat-soluble vitamin that performs multiple functions in the body. In addition to regulating calcium and phosphate levels in the body and contributing to bone mineralization, it participates in various brain and neurocognitive processes. In fact, the deficiency of this vitamin has also been linked to various psychiatric disorders, including depression.

Meta-analyses of Depression

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Depression summary

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