Depression is often associated with low D and treated by Vitamin D

Depression and Vitamin D: A Peculiar Relationship

Cureus. 2022 Apr 21;14(4):e24363. doi: 10.7759/cureus.24363

Nisha Saji Parel 1, Parimi Vamsi Krishna 2, Anuradha Gupta 3, Kamsika Uthayaseelan 4, Kivonika Uthayaseelan 5, Monika Kadari 6, Muhammad Subhan 7, Sripada Preetham Kasire 8

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Randomized Controlled Trials

Depression is a psychiatric disorder characterized by various symptoms that can impact one's quality of life. Vitamin D, a fat-soluble vitamin, is well-known for its role in bone health, and research on its effects on mental health has only recently emerged. Vitamin D deficiency is widespread worldwide, and it has been linked to an increased risk of depression. In this article, we have discussed different hypotheses that explain the role of vitamin D in gene expression and its effects on neurotransmitters and different brain functions. We have reviewed literature that shows us that Vitamin D deficiency is a risk factor for depression and explored studies that show us the effects of using or supplementing Vitamin D in preventing depression among various populations.

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Intervention of Vitamin D for Depression

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Meta-analyses of Vitamin D and Depression

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VitaminDWiki - Depression summary

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VitaminDWiki - Suicide associated with low vitamin D - many studies contains

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