CYP27B1

The CYP27B1 gene activates Vitamin D in the Kidney,     Skin,     Lungs,     Brain,    Eyes    Breasts    etc.

Poor CYP27B1 is assocated with COVID,    Miscarriage,   Lupus,   Alz, ~hs~ ~hs~Parkinson, ~hs~ ~hs~MSA,   Rickets

CYtochrome P450 family 27 subfamily B member 1     = 25-Hydroxyvitamin D3 1-alpha-hydroxylase

• items in CYP27B1 category

• articles in the Genetics

• articles in Vitamin D Receptor

• articles in Vitamin D Binding Protein

• CYP27B1 and other genes are less activated in seniors

• CYP27B causes many health problems – March 2020

• Every Parkinson’s brain had a poor CYP27B1 gene

  What can be done if have a poor CYP27B1

• Larger doses of Vitamin D

• More Bio-available: Gut-friendly form, Topical form, taken with fatty meal, taken with evening meal

• Additional sources: UV

• Increase Vitamin D metabolism: additional Magnesium, Omega-3

  • All cytochrome P450 enzymes require Mg++ as a cofactor

• Increase the amount of Vitamin D in the blood that gets to cells: increase activation of VDR

  • See: Reasons for low response to vitamin D

  Vitamin D blood test misses CYP27B1 and other genes

Here are all of the CYP27B1 articles

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See also web

• Gene therapy for CYB27B1extended the lives of mice with acute myeloid leukemia - compared to placebo

  • A novel vitamin D gene therapy for acute myeloid leukemia

  • Behind paywall DOI: 10.1016/j.tranon.2020.100869 Sept 2020

• Higher risk of Atrial fibrilation of poor CYP27B1

  • Vitamin D Status in Patients with Atrial Fibrillation and Heart Failure - Is there a Link? - June 2021

  • Details are behind a paywall @ DOI: 10.7754/Clin.Lab.2020.200902

CYP27B1 Associations: Genetics 37, Vitamin D Receptor 33, Vit D Binding Protein 21, Cancer - Breast 4, Pregnancy 4, Vision 3 Cognitive 3, UV 3

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