Dr. Gominak in Texas has some interesting ideas about Migraine, Sleep and Vitamin D
see new publication by Dr. Gominak Nov 2011 Poor sleep and lack of vitamin D - Nov 2011
CLICK HERE for her web page on Migraine and Vitamin D
Notes from PDF CLICK HERE for PDF
- Migraine pain transmitters are mutant genes which turn on the pain receptors evolved to be activated only with concussions.
- If you do not have a migraine gene a sleep disorder will not cause headache pain.
- "Most patients with daily headache have a primary sleep disorder, either sleep apnea, restless leg syndrome or periodic limb movements of sleep.” Page 35
- 'Most of these patients have vitamin D deficiency with or without accompanying B12 deficiency
Measure D 25OH, B12, iron and replace all that are low (page 35)
- Vitamin D 70- -85 nanograms/ ml.
- B12 > 500/ml.“
Any migraine theory has to explain (page 37)
- Why do migraines start at puberty?
- Why do they start in boys and girls around the same age but get much better in boys?
- Why are they worse around the menses?
- Why are they much worse perimenopausally?
- Why do they go away after menopause?
See also in VitaminDWiki
- Vitamin D and Migraine – Nov 2010
- All items in category Headache and vitamin D
- Sleep and vitamin D - Jan 2011 also by Dr. Gominak
- Overview Brain and vitamin D
- Cluster headaches substantially reduced by 10,000 IU of Vitamin D in 80 percent of people
- Overview Magnesium and vitamin D
- Headache with vitamin D may mean you need Magnesium
- Google search migraine magnesium 2,000,000 hits May 2014
See also web
- FDA approved TMS device for headache - Dec 2013
Based on a single RCT and diary entries of 100 people
Side effects from the device were rare, the FDA said, but included "single reports of sinusitis, aphasia (inability to speak or understand language) and vertigo."
Rare? with only 100 people, Minor?
Wonder how many of the following RCT would get FDA approval if significant effort was applied?
Proven: Vitamin D prevents or treats 83 health problemsVitaminDWiki July 2017Go to http://is.gd/proofvitd to get details
- Proof that Vitamin D Works has the following summary
This is one of 8,000+ Vitamin D pages which can be read in any of 103 languages
Click on pink box in the upper right to select a language
Dec 2016 PDFs of this page (75 proofs) in No such attachment on this page No such attachment on this page No such attachment on this page No such attachment on this page No such attachment on this page No such attachment on this page No such attachment on this page No such attachment on this page
No such attachment on this pageHealth Problem
Reduction by Vit D
click for details
RCT = Random Controlled Trial
* = link to additional RCT CT = Clinical Trial
Hypertension T 149 to 142 mm Hg RCT* *, 2400 IU. 100,000 IU* Cardiovascular after attack T 32 % fewer deaths CT 1000 IU Diabetes Type 1 P 85 % 12000 kids, 2000 IU Diabetes Type 2 T 62 % RCT* CRP reduction, 4000 IU
Injection is far better - RCT *,
Back Pain T 95 %
60,000 IU weekly
Influenza P 90 % RCT *, 2000 IU Falls P 50% RCT, 100,000 IU monthly
RCT with Meals on Wheels 2016
Hip Fractures P 30 % RCT * 800 IU Rickets P 98 % Turkey, 400 IU NOT RCT, given to all children Raynaud's Syndrome T 40 % RCT, visual scale, 20000 IU Avg Menstrual pain P 76 % RCT, 7000 IU Avg, PMS reduced by half Pregnancy risks P 50 % RCT, 4000 IU C-section, unplanned P 50 % RCT, 4000 IU, small study Low birth weight P 60 % RCT * 1000 IU of D2 TB P 60 % RCT, 800 IU Breast Cancer P 60 % RCT, 1100 IU (2007) Rheumatoid Arthritis pain T 40 % RCT, 500 IU, added to prescription Cystic Fibrosis T 75 %
2nd study improved
RCT, pilot 4X fewer deaths 250,000 IU
RCT, pilot 8,200 IU
Chronic Kidney T 90 to 70 PTH RCT, 3500 IU, Respiratory Tract Infection P 63 % RCT, 4000 IU 1 year 2nd RCT: 2000/800 IU
3rd RCT 20,000 IU weekly
Lupus T zero flares Loading then 100,000 IU monthly, RCT too Sickle Cell T Less pain RCT, up to 100,000 IU/week Leg ulcer healing T 4X faster RCT, 50,0000 IU/week, small study Traumatic Brain Injury T 2X RCT, 20,0000 IU/day with progesterone Parkinson's Disease T Stabilized RCT, 1200 IU/day Multiple Sclerosis P 68% RCT, 7100 IU prevent pre-MS ==> MS Congestive Heart Failure T 90 % RCT, 1000 IU infants (also: Adults, not RCT) Middle Ear Infection P 30 % RCT, 1000 IU infants Gingivitis T 88 % RCT, 2000 IU Muscle in seniors T 17 % more muscle RCT, 4000 IU Antibiotic use when >70y T 47 % RCT, 60,000 IU monthly Infants taller Benefit 1 cm tall RCT, 50,000 IU weekly, 8 weeks Gestational Diabetes T Treated RCT, 2 doses of 50,000 IU After Heart Attack T +6% ejection fraction RCT, 800,000 IU one time Prostate Cancer T Fewer +cores RCT, 4000 IU (2012) Asthma P T Reduced symptoms RCT, 60K IU/month; RCT 50K IU/week
Meta-analysis of Asthma intervention
Need good D at 4 weeks into preg.
Depression T Reduced RCT, 300,000 IU injection RCT helped Prozac Low vitamin D
P All infants > 20 mg RCT, 5,000 IU Fibromyalgia T Reduced RCT, 30-48 ng RCT 50K IU/week Hives, Chronic T Reduced 40% RCT, 4000 IU added Cholesterol T Reduced 4 mg RCT, 400 IU + Ca Weight Loss T lost 5 more lbs RCT, 2000 IU +diet +exercise Multiple Sclerosis T 95% were CURED 20,000 to 140,000 IU/day Gestational Diabetes P 40% RCT * , 5,000 IU Chronic Obstructive
T 17X improvement CT, 50,000 IU weekly
RCT 100,000 IU monthly
Asthma T 1/2 Asthma attacks RCT >42 mg of vitamin D Quality of Life (QoL) T Nursing Home QoL CT, 4,000 IU in daily bread Death of Critically Ill Patients T 20% increase in survivability RCT 540 K IU loading than 90K monthly Restless Leg Syndrome T Score 26 ==> 10 CT, Vitamin D dose size not state in abstract Hepatitis-C T Enhanced conventional drugs RCT 2.000 IU Chron's disease T improved when > 30 ng
2nd study fewer relapses
RCT 2,000 IU
10,000 IU RCT
Pre-term birth P 2.5X decrease, also:
fewer c-section & better Apgar
RCT 2,000 IU India Lupus T Pain reduced RCT 4,000 IU Cluster headaches T CH eliminated in 60% 10,000 IU, Mg, Omega-3, etc Autism T 80% improved CT 300 IU/kg/day for 3 months PreDiabetes T ~20% reduced RCT 60,000 IU/month Weight loss:
Overweight and Obese
T 12 lbs in 6 months RCT 100,000 IU/month Sarcopenia = muscle loss T 27% increase RCT 1,000 IU Growing Pains T 60% decrease ~100,000 IU/month -NOT RCT, given to all
2nd study, similar results
Osteoarthritis pain T 60% decrease 50,000 IU/weekly - NOT RCT, given to all Amyotrophic Lateral Sclerosis T helped 2,000 IU - NOT RCT, given to all Vertigo T 3X reduction if raised > 10ng 600,000 IU load, then maint.
NOT RCT, given to all
Warts T 80% eliminated injection NOT RCT, given to all Metabolic Syndrome P reduced 44% when VitD
increased by 30 ng
NOT RCT, given to all Hay fever P reduced 48% 1,000 IU for 30 days RCT Preeclampsia P Reduced 50,000 IU every 2 weeksRCT Blood cell cancer
T Survival 90% vs 50% NOT RCT, given to all Irritable Bowel Syndrome T Reduced 3,000 IU spray RCT Urinary Tract Infection P 50% reduction RCT 20,000 IU weekly Mite Allergy P 5X reduction RCT 2,000 IU preg, 800 IU child Perinatal depression
(depression near birth)
T 50% reduction RCT 2,000 IU for just a few weeks Vaginosis T 10X reduction RCT 2,000 IU Eczema T Reduced 2 RCT 1,600 IU Non-Alcoholic
Fatty Liver Disease
T Reduced RCT 20,000 IU weekly Preclampsia T Reduced RCT 4,400 IU Knee Osteoartiritis T Pain Reduced RCT 60,000 IU monthly after loading dose Tuberculosis T Faster Recovery RCT single 450,000 IU dose Stroke - Ischemic T Faster Recovery RCT single 600,000 IU injection Sepsis T Reduce ICU and Hospital
length of stay by 7 days each
RCT 400,000 IU Trauma deaths T 50% fewer deaths Vitamin D & Glutamine
NOT RCT, given to all
Hemodialysis patients T helped 50,000 IU weekly NOT RCT, given to all Fatty liver - child T 2 X reduction Vitamin D & DHA RCT Fatigue T Reduced 100,000 IU single dose
NOT RCT, given to all
Note: virtually all of the above RCT proofs have a larger benefit that that shown for the TMS device
AND have far fewer side effects