Pages tagged with "Cyp2R1"

• Diabetes reduces Vitamin D - Mendelian randomization
• Vitamin D regulates 175 genes (in 8 categories)
• Why Vitamin D works differently for different people: genetics and epigenetics
• Schizophrenia associated with low Vitamin D and CYP2R1, CYP27B1, and CYP24A1
• Autoimmune diseases and poor Vitamin D genes – GC, CYP2R1, CYP27B1, and VDR
• Obese children have poor vitamin D genes (CYP27A1, CYP2R1, CYP27B1)
• CYP2R1 gene reduces response to Vitamin D - many studies
• High-fat diet reduces CYP2R1 gene needed to make semi-activated vitamin D (mice)
• COVID-19 5X worse if poor Vitamin D gene (CYP2R1)
• Hypothesis: Obesity reduces Vitamin D production by repressing CYP2R1 gene in liver and fat tissue
• The genetics of vitamin D
• Fasting and Diabetes both reduce Vitamin D activation (CYP2R1 in rodents)
• Lung Cancer (NSLC) more lethal if poor Vitamin D gene ( CYP2R1)
• Poor CYP2R1 gene reduces blood response to Vitamin D supplementation
• Response to Vitamin D varied by 12 ng due to gene variants (CYP2R1)
• CYP2R1 gene problem increases Multiple Sclerosis risk by 1.4X
• Breast Cancer far more likely in the sister having poor Vitamin D binding protein or poor CYP2R1 gene
• CYP2R1 (vitamin D 25-hydroxylase ) semiactivates vitamin D in many places in the body
• CYP2R1 mutations also cause vitamin D-deficient rickets
• CYP2R1 and GC variations decrease vitamin D response – PHD thesis