Youths need 1500 IU to get even 20 ng of vitamin D – RCT

Estimations of Dietary Vitamin D Requirements in Black and White Children

Pediatric Research (2016) doi:10.1038/pr.2016.46, Received 12 October 2015,

Accepted article preview online 09 March 2016

Kumaravel Rajakumar, Charity G Moore, Jonathan Yabes, Flora Olabopo, Mary Ann Haralam, Diane Comer, Michael F Holick & Susan L Greenspan

Age 8-14 - 6 month trial using 1,000 IU | | | | | --- | --- | --- | | Dose | Vitamin D
Level | % achieve | | 581 IU
IoM=600 IU | 12 ng | 90% | | 1543 IU | 20 ng | 90% | | 2100 IU | 20 ng | 97.5% |
Strange that no mention was made of obesity of youths See also VitaminDWiki * Obese teens need more than 2,000 IU of vitamin D for 3 months– RCT Feb 2015 * 2000 IU vitamin D raised virtually all Lebanese youths above 20 ng – RCT Oct 2013 * Pediatric trials of high dose vitamin D -163 are in a single online database – Feb 2016 * Third study found that Infants needed 1600 IU of vitamin D – JAMA RCT May 2013 * Note- infants should need less than youths as they weigh less * Vitamin D deficiency and childhood obesity: interactions, implications, and recommendations (5,000 IU) – Feb 2016

Background:

The Institute of Medicine (IOM) dietary guidelines for vitamin D are based on limited pediatric data. Our objective was to estimate the dietary vitamin D requirements for maintaining serum 25-hydroxyvitamin D [25(OH)D] concentrations at the various IOM-considered thresholds of vitamin D status (12, 16, and 20 ng/mL) during fall and winter in children.

Methods:

Ninety-six healthy 8- to 14-yr-old Pittsburgh-area black and white children enrolled in a randomized, placebo-controlled trial of vitamin D3 1000 IU daily for 6 months with baseline and 2 month follow-up assessments completed during October through April were studied. Vitamin D intake from diet and study supplement adjusted for adherence and serum 25(OH)D were measured.

Results:

The vitamin D intakes needed to maintain serum 25(OH)D concentrations at 12, 16, and 20 ng/mL in 90% of the children were 581, 1062, and 1543 IU/day, respectively. The estimated vitamin D intakes needed to maintain serum 25(OH)D concentrations at 20 ng/mL in 97.5% of the children was 2098 IU/day.

Conclusion:

Our data suggest that the current vitamin D recommended dietary allowance (RDA) (600 IU/day) is insufficient to cover the skeletal health needs of at least 50% of black and white children.

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Tags: Youth