Unknowns

From Henry Lahore - administrator of the VitaminDWiki

After reading over 5,000 papers on vitamin D I feel that some topics fall into one of the following categories

Updated Aug 2012

LACK CONSENSUS

  • Dark Skin and vitamin D

    • How much vitamin D is needed by people with dark skins?

    • How many generations does it take for a family with dark skin to adapt to high latitudes?

  • Vitamin A - consensus that too much is bad, but lack consensus about needing some with vitamin D

UNKNOWN

  • Why do 10% of the people who have >60 ng/ml need so little vitamin D to maintain that level?

  • Why does it only take < 1 minute of UV to greatly increase the vitamin D in mushrooms and carrots?

  • Toxic reaction to vitamin D is very rare - but how often is the "toxic" reaction due to a lack of co-factors?

  • Should the vitamin D level remain constant throughout the year?

    • Evolution appears to indicate that the vitamin D level should vary with the season
  • UV and vitamin D

    • For some conditions it appears that UV better than vitamin D (e.g. MS)

    • For other conditions it appears that Vitamin D needs UV as well