Some diseases reduce vitamin D getting to blood or cells

Some diseases restrict vitamin D by changing gene activation,
    by one or more of the following

• Restrict conversion of light into vitamin D in the skin

• Restrict oral absorption in the gut

• Restrict semi-activation in the liver

• Restrict free semi-activated vitamin D from getting to the kidneys

• Restrict full activation in the kidneys

• Restrict semi and fully activation in the cells

• Restrict activated Vitamin D from entering cell mitochondria (VDR)

• Destroy the vitamin D before it gets to the cells

  Some diseases restrict vitamin D without changing genes

• The disease just uses/consumes the vitamin D

• The disease upsets the gut, which reduces bioavailability of oral form

  • unless a gut-friendly form is used

  References

• COVID changes 100 vitamin D-related genes in the lungs

• Reasons for low response to vitamin D

• Genetics category has items along with related searches

• The risk of 44 diseases at least double with poor VDR as of Oct 2019