Response to weekly Calcifediol in 4 months - RCT

Randomised Trial to Evaluate the Efficacy and Safety of Calcifediol vs Placebo in Subjects With Vitamin D Deficiency (WORFEROL)

📄 PDF of the trial registration as of July 2021

Note: This is a test vs placebo, not vs standard vitamin D

Note: Study is looking at response in 16 weeks, rather than the very fast response reported in a single trial

See also VitaminDWiki:  Note: Calcifediol = Calcidiol

• Vitamin D3 becomes Calcidiol which becomes Calcitriol

• Calcidiol increased blood levels of Vitamin D in one month (dogs) – Feb 2021

• Weekly response to semi-activated vitamin D slightly better than standard – RCT Nov 2019

  • seems like the Nov 2019 study is better - compares Calfediol to Vitamin D

• Semi-activated Vitamin D given weekly (used by Spanish COVID-19 trial) – US patent application Sept 2020

• COVID-19 defeated by calcifediol form of Vitamin D in Spain - pilot RCT Aug 29, 2020

• Is calcidiol a better form of vitamin D for some animals and maybe humans with liver problems

• Calcifediol (Calcidiol) might be a better form of Vitamin D for some people – May 2019

• Pigs have about 2X less variation in response to calcidiol as humans do to vitamin D – 2015

• Vitamin D levels might be raised very quickly the following chart is from a patent application

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  Getting Vitamin D into your blood and cells has the following chart

Calcidiol category listing has items along with related searches

• Calcidiol is available only by prescription and is expensive

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• Has about a 1 month response time