People from the Indian continent living in the UK continue to have extremely low levels of Vitamin D

Created July 2020

Very High Prevalence of 25-hydroxyvitamin D Deficiency in n 6433 UK South Asian adults: analysis of the UK Biobank Cohort

Br J Nutr. 2020 Jul 22;1-34. doi: 10.1017/S0007114520002779

Andrea L Darling 1, David J Blackbourn 1, Kourosh R Ahmadi 1, Susan A Lanham-New 1

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Items in both categories Dark Skin and Europe are listed here: {category} --- COVID-19 more frequent and deadly for those with dark skins (high risk of low vitamin D) * Lack of vitamin D closely associated with black health disparities – Nov 2010 * 10 health problems associated with Dark Skin (low vitamin D) Overview Dark Skin and Vitamin D contains the following summary {include} Blacks die more often than whites of many diseases (they have less vitamin D) – 2012 contains the following summary {include}

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Little research has assessed serum 25-hydroxyvitamin D (25(OH)D) concentration and its predictors in western dwelling South Asians in a relatively large sample size. This observational, cross-sectional analysis assessed baseline prevalence of 25(OH)D deficiency in UK dwelling South Asians (aged 40-69 years, 2006-2010) from the UK Biobank cohort. Serum 25(OH)D measurements were undertaken using the DiaSorin Liaison XL assay. Of n 6433 South Asians with a 25(OH)D measurement, using commonly used cut-off thresholds, 55% (n 3538) had 25(OH)D <25 nmol/L (severe deficiency) and 92% (n 5918) had 25(OH)D <50 nmol/L (insufficiency). Twenty per cent (n 1287) had 25(OH)D concentration <15 nmol/L (very severe deficiency). When n 824 participants with undetectable (<10 nmol/L) 25(OH)D measurements were included (total n 7257), 29% (n 2105) had 25(OH)D <15 nmol/L, 60% (n 4354) had 25(OH)D <25 nmol/L and 93% (n 6749) had 25(OH)D < 50 nmol/L. Logistic regression predictors of 25(OH)D <25 nmol/L included the following characteristics: being male; Pakistani; higher body mass index; 40-59 years old; never consuming oily fish; summer sun exposure < 5 hours per day, not using a vitamin D containing supplement, measurement in winter or spring and vegetarianism. In terms of region, median 25(OH)D concentration was 19-20 nmol/L in Scotland, Northern England, the Midlands and Wales. Across Southern England and London it was slightly higher at 24-25 nmol/L. Our analyses suggest the need for increased awareness of vitamin D deficiency in South Asians as well as urgent public health interventions to prevent and treat vitamin D deficiency in this group.

Tags: Darker Skin Europe