Multiple Sclerosis and Vitamin D chapter (Coimbra and Brazil not mentioned)

Created October 2019

Vitamin D and Multiple Sclerosis

Clinical Neuroimmunology pp 197-212

Part of the Current Clinical Neurology book series (CCNEU)

Michael J. Bradshaw Michael F. Holick James M. Stankiewicz

Dr. Holick (a co-author) was very impressed during va isit to Dr. Coimbra in Brazil about 5 years ago Dr. Coiumbra's great success with >150 ng of vitamin D is not mentioned here Perhaps because no clinical trials are involved. This chapter recommends only 40-70 ng of vitamin D This chapter does not appear to mention the extremely important cofactors - such as Magnesium Multiple Sclerosis and (lots of) Vitamin D - book by patient on Coimbra protocol - Feb 2016 contains protocol description {include}

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Table of Contents

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Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. Much has been learned about the role of vitamin D in MS, although our understanding remains incomplete. While the precise etiology of MS remains incompletely understood, low vitamin D status is one factor that appears to predispose to the development of MS, and patients with low 25(OH)D levels may be at greater risk of disease activity. Clinical trials are currently underway to more directly address the role of vitamin D supplementation in MS, yet further investigations are needed. This chapter reviews the role of vitamin D in the pathophysiology of MS and the evidence related to clinical outcomes in patients with MS who have vitamin D deficiency.

Tags: Multiple Sclerosis