Magnesium – the common test does not show deficiency

Magnesium: Are We Consuming Enough?

Nutrients 2018, 10(12), 1863; https://doi.org/10.3390/nu10121863

Mohammed S. Razzaque 1,2,3,4

1 Department of Pathology, Lake Erie College of Osteopathic Medicine, Erie, PA 16509, USA

2 Department of Oral Health Policy & Epidemiology, Harvard School of Dental Medicine, Boston, MA 02115, USA

3 Department of Preventive & Community Dentistry, School of Dentistry, College of Medicine & Health Sciences, University of Rwanda, Kigali, Rwanda

4 College of Advancing & Professional Studies (CAPS), University of Massachusetts Boston (UMB), Boston, MA 02125, USA

(This article belongs to the Special Issue Nutritional Status and Bone Health)

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Magnesium is essential for maintaining normal cellular and organ function. In-adequate magnesium balance is associated with various disorders, such as skeletal deformities, cardiovascular diseases, and metabolic syndrome. Unfortunately, routinely measured serum magnesium levels do not always reflect total body magnesium status. Thus, normal blood magnesium levels eclipse the wide-spread magnesium deficiency. Other magnesium measuring methods, including the magnesium loading test, may provide more accurate reflections of total body magnesium status and thus improve identification of magnesium-deficient individuals, and prevent magnesium deficiency related complications.

Magnesium Tests

Total serum magnesium -The most popular test, but only measures 1% of body content

Oral magnesium loading test

Intravenous magnesium loading test

RBC (red blood cell) magnesium content

Hair magnesium content

Muscle magnesium content (biopsy)

Bone magnesium content

24-h urinary magnesium

The ratio of ionized to total magnesium

Tags: Magnesium