Low-dose vitamin D does not help cardiovascular (many were 100-1,000 IU) – meta-analysis

Created June 2019

Vitamin D Supplementation and Cardiovascular Disease Risks in More Than 83 000 Individuals in 21 Randomized Clinical Trials -A Meta-analysis

JAMA Cardiol. Published online June 19, 2019. doi:10.1001/jamacardio.2019.1870

1. # Yup, <2,000 IU has virtually no detectable CV benefit, need 4,000+ IU 1. Other Cardiovascular Meta-analyses as of june 2019 Low Dose, No Benefit * Small or infrequent doses of vitamin D do not reduce heart failure much – meta-analysis Jan 2018 * Chronic Heart Failure not treated by Vitamin D, if dose size is ignored – meta-analysis Oct 2015 * 800 IU Vitamin D does not help heart – meta-analysis Aug 2011 High Dose, Yes Benefit * Vitamin D supplementation reduces many Cardiovascular Disease markers– meta-analysis July 2018 * Heart Failure and Vitamin D meta-analyses - many studies * C-reactive protein (heart disease marker) reduced by vitamin D – meta-analysis 2014, 2019 Low Vitamin D, Cardiovascular problems * Peripheral arterial disease risk is 1.5X higher if low vitamin D – meta-analysis March 2018 * Peripheral Arterial Disease patients have low vitamin D levels – meta-analysis Oct 2015 * Cardiovascular deaths 12 percent less likely if have 10 ng more vitamin D – meta-analysis March 2017 * Atrial Fibrillation 1.3 times more likely if low vitamin D – meta-analysis Sept 2016 * Cardiovascular disease 50 % more likely if low vitamin D - meta-analysis Nov 2012 * Half as many heart deaths for those with high levels of vitamin D – meta-analysis Sept 2012 * Shift workers 23 percent more likely to have cardiovascular events – meta-analysis July 2012 Poor Vitamin D Genes, Cardiovascular Problems * Coronary Artery Disease without diabetes 5 times more likely if VDR gene problems – meta-analysis May 2016 Items in both categories Cardiovascular and Intervention are listed here: {category} --- 1. Cardiovascular category starts with the following {include}

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Titles of articles reporting on this poor study

      JAMA has a great press release system

The Demise of Vitamin D for Cardiovascular Prevention = JAMA editorial

Vitamin D may not help your heart - Medical Xpress

No cardiovascular benefit from vitamin D supplementation

Vitamin D Use Does Not Reduce Risk of Cardiovascular Disease

New study suggests Vitamin D has no impact on heart health

Vitamin D Supplements Not Associated with Lower CVD Risks

Vitamin D supplementation fails to reduce major adverse CV events

Vitamin D for CV Risk? Think Twice, Meta-analysis Confirms

Vitamin D supplements may not reduce the risk of cardiovascular disease

Forget Vitamin D Supplements for Heart Disease

Meta-Analysis Does Not Link Vitamin D Supplements, Drop in MACE

Forget the vitamin D when it comes to CVD

Vitamin D does NOT prevent heart disease, study finds

Study: Vitamin D Supplements Don’t Lower Risk For Heart Disease

Popping a vitamin D supplement for heart benefits? It might not help at all

Study Disproves Common Belief in Vitamin "D"!

Lack of effect: Massive meta-analysis reports no heart benefits for vitamin D supplements

Vitamin D does zilch for CVD prevention: meta-analysis

Vitamin D not protective against cardiovascular events

21 trials
45% used only 100-1,000 IU
14% dosing interval was too long (3+ months)
14% did not use Vitamin D

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Short URL= is.gd/CardioMeta

Tags: Cardiovascular Meta-analysis