Hypothesis: Poor Vitamin D Binding protein may increase COVID-19 risk

Created March 2021

A genetic insight into vitamin D binding protein and COVID-19

Medical Hypotheses; Volume 149, April 2021,https://doi.org/10.1016/j.mehy.2021.11053

lMona Alshahawey

1. # Items in both categories Vitamin D binding Protein and virus: {category} 1. Vitamin D Binding Protein category listing has items and the following introduction {include} 1. Vitamin D Binding Protein has a list of health problems {include} 1. Genetics category contains the following {include}

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It’s since December 2019 that Corona virus disease (COVID-19) has emerged to be the global issue of concern. A “pandemic”; this is what WHO has declared about the COVID-19 outbreak on March 3rd, 2020. Vitamin D and its deficiency have recently been claimed to be one of the potential factors affecting COVID-19 risks and outcomes ^{^[1]}. As Selberstein et al., has recently discussed the effect of vitamin D deficiency, and the role of vitamin D supplementation in COVID-19 patients ^{^[2]}, I’d believe that vitamin D binding protein (DBP) is maybe also involved. A closer look on DBP and its action on regulating the circulatory vitamin D levels, its polymorphisms and their impact on COVID-19 prevalence and mortality, will be briefly discussed.

Tags: Virus Vit D Binding Protein