Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues

Created November 2012

For 40+ years Cardiovascular problems associated with low Magnesium

Magnesium and Vitamin D are synergistic, that is, increasing one helps the other.
Magnesium not Magnesium
Vitamin D Magnesium or Vitamin D
Aging, Amytrophic Lateral Sclerosis, Alzheimer's Disease;
Asthma, Attention Deficit Disorder; Autism, Cancer, Cerebrovascular,
Chronic Fatigue, Diabetes, Hearing Loss, Heart Disease. Heart Attack, Atherosclerosis,
Cardiovascular Disease , HIV, AIDS; Hypertension; Kidney Stones,
Migraine Headache, Multiple Sclerosis, Obesity, Osteoporosis; Peripheral vascular disease;
Pregnancy-related problems,Rheumatoid Arthritis; Sports-related problems,
Vitamin D only

Acne, Allergy, Autoimmune, Bone, Breathing,
Celiac, Cognition, Colds and Flu, Cystic Fibrosis,
Dental, Fertility, Hyperparathyroid, Immunity, Kidney,
Liver, Lupus, Osteoarthritis, Pain - chronic, Parkinson,
Psoriasis, Rickets, Strokes, Sarcoidosis, Thyroid, Parathyroid,
Tuberculosis, Vision, Hair, Skin, Sports | | Not Vitamin D | Magnesium only
Aggressive Behavior, Alcoholism, Arrhythmia, Cerebral Palsy,
Chemical Sensitivity, Cluster Headaches; Cocaine-related Stroke; Constipation,
Cramps, Fluoride Toxicity; Head Injuries, Central Nervous System Injuries,
Magnesium Deficiency; Menopause, Mitral Valve Prolapsee,
Nystagmus, Psychiatric Disorders; Repetitive Strain Injury, Sickle Cell Disease, SIDS,
Stress, Stuttering, Tetanus; Tinnitis, Sound Sensitivity; TMJ; Toxic Shock; Violence | Neither
ALL OTHER DISEASES |

Items in both VitaminDWiki categories of Cardiovascular and Magnesium:

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See also: VitaminDWiki and Web

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Items in both categories Cardiovascular and Omega-3 are listed here:

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Note: Increasing intake does not change Omega-3 index much if consume lots of Omega-6

Atrial Fibrillation: Vitamin D genes, etc

Afib 1.8 X more likely if poor Vitamin D Binding Protein

Genetically deprived vitamin D exposure predisposes to atrial fibrillation - 2017

Europace. 2017 Dec 1;19(suppl_4):iv25-iv31. doi: 10.1093/europace/eux312.

Chan YH1, Yiu KH1,2, Hai JJ1, Chan PH1, Lam TH3, Cowling BJ3, Sham PC4, Lau CP1, Lam KS2,5, Siu CW1,2, Tse HF1,2.

In VitaminDWiki as Atrial Fibrillation strongly associated with some vitamin D binding protein – Dec 2017

📄 Download the PDF from VitaminDWiki

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AIMS: Low vitamin D level is associated with atrial fibrillation (AF) and may be implicated in its pathogenesis.

METHODS AND RESULTS:

We studied single nucleotide polymorphisms (SNPs) of vitamin D mechanistic pathways and serum 25-hydroxyvitamin D [25(OH)D] levels in an age- and gender-matched case-control study (controls without AF: mean age 68.6 ± 8.7 years, female 25%; n = 1019; with AF: mean age 69.7 ± 9.5 years, female 30%; n = 156) recruited from a Chinese clinical cohort of patients with stable coronary artery disease. Twelve SNPs involved in the vitamin D mechanistic pathways were studied [biosynthetic: rs4646536, rs10877012, rs3829251, rs1790349; activation: rs2060793, rs1993116; vitamin D-binding protein (VBP)/group-specific component (GC): rs4588, rs7041, rs2282679, rs1155563; and vitamin D receptor: rs1544410, rs10735810]. A genetic risk score (GRS) (0-8) was constructed from SNPs associated with serum 25(OH)D as a proxy to lifelong vitamin D-deficient state.

All 4 SNPs involved in the VBP/GC were significantly associated with serum 25(OH)D (rs4588, P < 0.001; rs2282679, P < 0.001; rs7041, P = 0.011; rs1155563, P < 0.001; all other SNPs, P > 0.05). Vitamin D GRS (points 0-8) generated from these 4 SNPs was independently predictive of serum 25(OH)D [B = 0.54, 95% confidence interval (CI) 0.30-0.79; P < 0.001]. Genetically deprived vitamin D status as denoted by a low GRS (0-3) independently predicted an increased risk of AF, compared to a high GRS (4-8) ( odds ratio = 1.848 , 95% CI 1.217-2.805; P = 0.004).

CONCLUSION: Genetically deprived vitamin D exposure predisposes to increased AF among patients with coronary artery disease. Whether VBP/GC may alter the risk of AF via alternative mechanisms warrants further studies.

Vit D Binding Protein category listing has items along with related searches

Note: Vitamin D Binding Protein problems are NOT noticed by Vitamin D blood test

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Cardiovascular category in VitaminDWiki starts with the following

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This page was renamed Dec 2018. There have actually been visitors to this page since it was originally made

Tags: Cardiovascular Magnesium Omega-3 Vit D Binding Protein