Dementia 2X more likely after ICU (suspect low Vitamin D)

ICU stays linked to a doubling of dementia risk

MDEdge

• "The Rush team assessed the impact of an ICU stay on dementia risk in 3,822 older adults (mean age, 77 years) without known dementia at baseline participating in five diverse epidemiologic cohorts."

• "In models further adjusted for other health factors such as vascular risk factors and disease, other chronic medical conditions and functional disabilities, the association was even stronger: ICU hospitalization was associated with roughly double the risk of Alzheimer’s dementia (HR 2.10 ; 95% CI, 1.66-2.65) and all-type dementia (HR, 2.20 ; 95% CI, 1.75-2.77)."

  • Vitamin D was NOT mentioned as a possibility

  Surgery is known to cut Vitamin D levels in half in 2-3 days

• Vitamin D levels crash after various surgeries (cardiac in this case) – Nov 2021

• Post-surgery delirium in critically ill 1.4X more likely for each 10 ng lower level of vitamin D (below 30 ng) – July 2021

• Vitamin D levels dropped 42 percent immediately after pediatric cardiac surgery – Dec 2019

• Surgeries often deplete Vitamin D - 300,000 IU resulted in little response – Nov 2018

• Critical illness – Vitamin D levels start low and then drop for several days – Feb 2018

Trauma/Surgery pages with DEMENTIA in title (2 as of Aug 2022)

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VitaminDWiki pages with DEMENTIA in title (xx as of Aug 2022)

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