ADHD associated with significantly less Vitamin B12

Created September 2018

Homocysteine, Pyridoxine, Folate and Vitamin B12 Levels in Children with Attention Deficit Hyperactivity Disorder.

Psychiatr Danub. 2018 Sep;30(3):310-316. doi: 10.24869/psyd.2018.310.

Altun H1, Şahin N, Belge Kurutaş E, Güngör O.

Dept. of Child and Adolescent Psychiatry, Faculty of Medicine, Kahramanmaras Sutcu Imam U., Kahramanmaras, Turkey, drhaticealtun@gmail.com.

| | | | | | --- | --- | --- | --- | | | ADHD (n=30) | Controls (n=30) | p | | Vitamin B12 (pg/mL) | 260 | 389 | <0.001 | * Deficiencies of Vitamin D, Iron, Magnesium, and Zinc all associated with ADHD – Sept 2014 * Drugs which create deficiencies in Vitamin D, Vitamin K, Magnesium, Zinc, Iron, etc. – Sept 2017 * Hypothesis – Vitamin B-12 deficiency is associated with Vitamin D deficiency * Study on this page did not check for Vitamin D deficiency * Vitamin D (also B9, B12, C, E, and K) can be limited by genes – April 2017 * * ADHD and Vitamin D Deficiency category listing has items along with related searches * Vitamin B12 category listing has items along with related searches** The following is looking for possible associations Items in both categories B12 and Omega-3 are listed here: {category} Items in both categories ADHD and Omega-3 are listed here: {category} Items in both categories ADHD and Magnesium are listed here: {category}

PDF is available free at Sci-Hub   10.24869/psyd.2018.310

BACKGROUND:

In our study, we aimed to evaluate the serum homocysteine levels, pyridoxine, folate and vitamin B12 levels in children with attention deficit hyperactivity disorders (ADHD).

SUBJECTS AND METHODS:

This study included 30 newly diagnosed drug-naive children with ADHD (23 males and 7 female, mean age 9.3±1.8 years) and 30 sex-and age matched healthy controls. The diagnosis of ADHD was made according to DSM-V criteria. Children and adolescents were administered the Schedule for Affective Disorders and Schizophrenia for School Aged Children, Present and Lifetime Version, the Conners' Parent Rating Scale-Revised, Long Form, the Conners' Teacher Rating Scale and the Wechsler Intelligence Scale for Children Revised (WISC-R) for all participants. Homocysteine, pyridoxine, folate and vitamin B12 levels were measured with enzyme-linked immunosorbent assay.

RESULTS:

Homocysteine, pyridoxine, folate and vitamin B12 levels were significantly lower in children with ADHD compared with their controls (p<0.05). A positive significant correlation was observed between the all WISC-R scores and vitamin B12 level in patients (r=0.408, p=0.025).

CONCLUSIONS:

The results obtained in this study showed that reduced homocysteine, pyridoxine, folate and vitamin B12 levels could be a risk factor in the etiology of ADHD.

Tags: ADHD B12