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Benjamin Udoka Nwosu, Louise Maranda, Ninfa Candela
Vitamin D status in pediatric irritable bowel syndrome
www.plosone.org
www.plosone.org
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BT
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1 TL
-0.004 Tc
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(percen-)Tj
-34.4747 -1.2982 Td
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(and)Tj
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(obesity)Tj
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0 Tc
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(95)Tj
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q
1 j
1 J
0 w
7.4999 0 0 6.6659 371.622 685.8708 cm
BT
/F7 1 Tf
1 TL
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(th)Tj
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Q
q
1 j
1 J
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1 TL
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1 TL
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q
1 j
1 J
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1 TL
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(25\(OH\)D)Tj
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(chemiluminescent)Tj
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(immunoassay)Tj
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(\(DiaSorin)Tj
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(Minnesota\),)Tj
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(serum)Tj
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(25\(OH\)D)Tj
ET
Q
q
1 j
1 J
0 w
7.4999 0 0 6.6659 272.5795 581.6125 cm
BT
/F7 1 Tf
1 TL
-0.0053 Tc
0 0 Td
(2)Tj
ET
Q
q
1 j
1 J
0 w
10 0 0 10 278.3622 583.2566 cm
BT
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1 TL
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(and)Tj
1.7291 0 Td
(25\(OH\)D)Tj
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Q
q
1 j
1 J
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7.4999 0 0 6.6659 334.4314 581.6125 cm
BT
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1 TL
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(3)Tj
ET
Q
q
1 j
1 J
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10 0 0 10 338.0031 583.2566 cm
BT
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1 TL
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0.4478 0 Td
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0.8561 0 Td
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1.542 0 Td
(an)Tj
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(intra-)Tj
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(and)Tj
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(inter-assay)Tj
4.5241 0 Td
(coefficients)Tj
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(and)Tj
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(a)Tj
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(functional)Tj
4.3085 0 Td
(sensitivity)Tj
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(of)Tj
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(10)Tj
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(nmol/L.)Tj
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1.7858 0 Td
(characterization)Tj
-28.7657 -1.2983 Td
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(vitamin)Tj
3.3108 0 Td
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(status)Tj
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(this)Tj
1.6724 0 Td
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1.7858 0 Td
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4.405 0 Td
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(which)Tj
2.6476 0 Td
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3.3108 0 Td
(D)Tj
0.9581 0 Td
(status)Tj
2.5001 0 Td
(using)Tj
2.3867 0 Td
(serum)Tj
2.7213 0 Td
(25\(OH\)D)Tj
4.1045 0 Td
(values)Tj
2.6646 0 Td
(as)Tj
1.0148 0 Td
(follows:)Tj
3.2881 0 Td
(vitamin)Tj
3.3109 0 Td
(D)Tj
-33.8397 -1.2983 Td
(deficiency)Tj
/F11 1 Tf
0 Tc
4.2633 0 Td
(<)Tj
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-0.004 Tc
0.9921 0 Td
(20)Tj
1.1735 0 Td
(ng/mL)Tj
2.9197 0 Td
(\(50)Tj
1.5137 0 Td
(nmol/L\),)Tj
3.7756 0 Td
(insufficiency)Tj
5.3064 0 Td
(2029.9)Tj
3.3392 0 Td
(ng/mL)Tj
2.9254 0 Td
(\(5074.5)Tj
3.6793 0 Td
(nmol/L\),)Tj
3.7757 0 Td
(and)Tj
-33.6639 -1.2982 Td
(sufficiency)Tj
/F6 1 Tf
0 Tc
4.49 0 Td
()Tj
/F7 1 Tf
-0.004 Tc
0.9922 0 Td
(30)Tj
1.1735 0 Td
(ng/mL)Tj
2.9197 0 Td
(\(75)Tj
1.5136 0 Td
(nmol/L\)[)Tj
0.83 0.64 0.02 0 k
(12)Tj
0 g
(].)Tj
5.4027 0 Td
(This)Tj
1.99 0 Td
(characterization)Tj
6.6613 0 Td
(is)Tj
0.8447 0 Td
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2.9877 0 Td
(to)Tj
1.0262 0 Td
(the)Tj
1.4683 0 Td
(classification)Tj
-31.4699 -1.3039 Td
(of)Tj
1.0148 0 Td
(vitamin)Tj
3.3108 0 Td
(D)Tj
0.9525 0 Td
(status)Tj
2.5001 0 Td
(by)Tj
1.1849 0 Td
(the)Tj
1.4683 0 Td
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3.9457 0 Td
(of)Tj
1.0148 0 Td
(Medicine)Tj
3.9912 0 Td
(and)Tj
1.7291 0 Td
(the)Tj
1.4683 0 Td
(American)Tj
4.1953 0 Td
(Academy)Tj
3.9855 0 Td
(of)Tj
1.0148 0 Td
(Pediatrics)Tj
-31.7761 -1.2983 Td
(which)Tj
2.6475 0 Td
(denote)Tj
2.948 0 Td
(vitamin)Tj
3.3109 0 Td
(D)Tj
0.9581 0 Td
(deficiency)Tj
4.2632 0 Td
(as)Tj
1.0148 0 Td
(25\(OH\)D)Tj
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0 Tc
4.1045 0 Td
(<)Tj
/F7 1 Tf
-0.004 Tc
(50)Tj
1.9446 0 Td
(nmol/L;)Tj
3.4355 0 Td
(or)Tj
1.0942 0 Td
(sufficiency,)Tj
4.7168 0 Td
(25\(OH\)D)Tj
/F11 1 Tf
0 Tc
4.1046 0 Td
(>)Tj
/F7 1 Tf
-0.004 Tc
(50)Tj
-34.5427 -1.2983 Td
(nmol/L[)Tj
0.83 0.64 0.02 0 k
(13)Tj
0 g
(,)Tj
0.83 0.64 0.02 0 k
4.7225 0 Td
(14)Tj
0 g
(].)Tj
-3.5263 -1.3039 Td
(ESR)Tj
1.8879 0 Td
(analyzer,)Tj
3.77 0 Td
(Vesmatic)Tj
3.9458 0 Td
(20)Tj
1.1679 0 Td
(\(Clinical)Tj
3.6566 0 Td
(Data,)Tj
2.347 0 Td
(Inc.,)Tj
1.9843 0 Td
(Smithfield,)Tj
4.5864 0 Td
(RI\))Tj
1.5193 0 Td
(was)Tj
1.7008 0 Td
(used)Tj
2.058 0 Td
(to)Tj
1.0261 0 Td
(quantify)Tj
3.549 0 Td
(ESR)Tj
-34.3953 -1.2983 Td
(according)Tj
4.1839 0 Td
(to)Tj
1.0261 0 Td
(standard)Tj
3.7247 0 Td
(protocol.)Tj
3.8211 0 Td
(Beckman)Tj
3.9457 0 Td
(Coulter)Tj
3.2542 0 Td
(AU)Tj
1.644 0 Td
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3.0501 0 Td
(ALT)Tj
2.0523 0 Td
(procedure)Tj
4.3143 0 Td
(\(Beckman)Tj
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-35.3023 -1.2982 Td
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1.5364 0 Td
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1.9842 0 Td
(250)Tj
1.6441 0 Td
(S.)Tj
0.9241 0 Td
(Kraemer)Tj
3.736 0 Td
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2.2564 0 Td
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2.2506 0 Td
(CA)Tj
1.5703 0 Td
(92821,)Tj
2.8233 0 Td
(USA\))Tj
2.4548 0 Td
(was)Tj
1.7008 0 Td
(used)Tj
2.0579 0 Td
(to)Tj
1.0262 0 Td
(measure)Tj
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(ALT,)Tj
2.279 0 Td
(while)Tj
2.3698 0 Td
(albumin)Tj
-34.1912 -1.2983 Td
(concentrations)Tj
6.1795 0 Td
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2.1203 0 Td
(measured)Tj
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(in)Tj
1.0375 0 Td
(a)Tj
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(Roche/Hitachi)Tj
6.0378 0 Td
(917)Tj
1.6497 0 Td
(chemistry)Tj
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(analyzer)Tj
3.5433 0 Td
(\(Roche)Tj
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5.4368 0 Td
(Indianapolis,)Tj
5.4425 0 Td
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1.6384 0 Td
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(standard)Tj
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Q
q
1 j
1 J
0 w
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BT
/F0 1 Tf
1 TL
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(analyses)Tj
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Q
q
1 j
1 J
0 w
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BT
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1 TL
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(regression)Tj
4.32 0 Td
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1.8539 0 Td
(\(IBM)Tj
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Q
q
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1 J
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11.9999 0 0 11.9999 200.0125 209.0267 cm
BT
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(1)Tj
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(D)Tj
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0 Tc
1.0148 0 Td
()Tj
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(50)Tj
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3.2088 0 Td
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2.2677 0 Td
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0.7993 0 Td
(0.001\).)Tj
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