Vitamin D and Omega-3 Ineffective for Preventing Cancer and Heart Disease (too little was used)

Vitamin D and Fish Oils Are Ineffective for Preventing Cancer and Heart Disease

Reported by New York Times

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Update - analysis of VITAL Trial

When the VITAL trial was started VitaminDWiki, and many others, predicted

that it would be unlikely to find a benefit


See also Omega-3 in VitaminDWiki

See also VitaminDWiki

See also Omega-3 in the web


Comments on the VITAL study

Beware of false propaganda against supplements like vitamin D3

There were some negative results that made headlines but there were also a lot of positive results as well. Let's talk about them!

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  • It was an randomized controlled trial involving more than 25,800 people that were randomly assigned to one of four groups: one received 2,000 IU of vitamin D a day and a placebo, another took 1g of omega-3 fatty acids a day with a placebo, a third took both 2,000 IU of vitamin D and 1g of omega-3 a day, and the last group received two daily placebos. All volunteers took their assigned nutrients for approximately five years, and researchers logged everything from cancer diagnoses to major heart events including heart attack and stroke, as well as deaths from cancer and heart disease.

  • The large omega-3 and vitamin D trial found no difference between omega-3 and placebo for adverse heart outcomes combined (heart attack + stroke) but it did find that fish oil reduced heart attack risk by 28% and 40% in people with low fish intake compared to placebo. The large omega-3 and vitamin D trial found no difference between omega-3 and placebo for adverse heart outcomes combined but it did find that fish oil reduced heart attack risk by 28% and 40% in people with low fish intake (less than 1.5 servings per week) compared to placebo. The reduction of heart attack risk among those taking omega-3s was especially pronounced among African American participants, with a 77% reduction was observed.

  • As for vitamin D no effect was found on heart attacks. There was a non-significant difference in reduced cancer rates compared to placebo. However, when the team examined rates after participants had been taking supplements for at least two years, they found that cancer deaths were significantly reduced by 25 percent among those taking vitamin D .

  • No serious side effects, such as bleeding, high blood calcium levels, or gastrointestinal symptoms were found with either supplement. The two supplements did not appear to interact with each other or have synergistic effects.