T1 Diabetes 35 percent more likely if 10 degrees further from equator (less vitamin D)

Spatial and temporal variation in type 1 diabetes incidence in Western Australia from 1991 to 2010: Increased risk at higher latitudes and over time.

Health Place. 2014 Jun 9;28C:194-204. doi: 10.1016/j.healthplace.2014.05.004. [Epub ahead of print]

Ball SJ1, Haynes A2, Jacoby P3, Pereira G4, Miller LJ5, Bower C6, Davis EA7.

1 Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia. Electronic address: stephen.ball@telethonkids.org.au.

2 Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia; Department of Endocrinology and Diabetes, Princess Margaret Hospital, Roberts Road, Subiaco, WA 6008, Australia. Electronic address: aveni.haynes@health.wa.gov.au.

3 Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia. Electronic address: peter.jacoby@telethonkids.org.au.

4 Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia; Yale Center for Perinatal, Pediatric and Environmental Epidemiology, Yale University, One Church Street, 6th Floor, New Haven, CT 06510, USA. Electronic address: gavin.pereira@telethonkids.org.au.

5 Public Health & Clinical Services Division, Western Australian Department of Health, 189 Royal St, East Perth, WA 6004, Australia. Electronic address: laura.j.miller2@health.wa.gov.au.

6 Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia. Electronic address: carol.bower@telethonkids.org.au.

7 Telethon Kids Institute, The University of Western Australia, 100 Roberts Road, Subiaco, WA 6008, Australia; Department of Endocrinology and Diabetes, Princess Margaret Hospital, Roberts Road, Subiaco, WA 6008, Australia. Electronic address: elizabeth.davis@health.wa.gov.au.

This study analysed spatial and temporal variation in childhood incidence of type 1 diabetes mellitus (T1DM) among Western Australia׳s 36 Health Districts from 1991 to 2010. There was a strong latitudinal gradient of 3.5% (95% CI, 0.2-7.2) increased risk of T1DM per degree south of the Equator, as averaged across the range 15-35° south. This pattern is consistent with the hypothesis of vitamin D deficiency at higher latitudes.

In addition there was a 2.4% (95% CI, 1.3-3.6) average increase in T1DM incidence per year.

These effects could not be explained by population density, socioeconomic status, remoteness or ethnicity.


Increase about 27 % (compounding 2.4% for a decade

See also VitaminDWiki

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Dr. Holick video on vitamin D - March 2013 video has the following

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See also web