COVID-19 patients who happened to be taking Vitamin D did much better

Created October 2020

~~#00F:Unfortunately, the Spanish study did not report how much Vitamin D some COVID-19 patients had been taking

Those taking Vitamin D had fewer health problems

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Those taking Vitamin D had much better outcomes

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Those with Vitamin D had much higher levels of vitamin D

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Comment by VitaminDWiki

  1. Many people taking a lot of Vitamin D did not get any COVID-19 infection

  2. People taking less Vitamin D got COVID-19, but did not have to go to the hospital

  3. People taking a small amount of Vitamin D entered the hospital, and were reported in this study

This paper was also reported elsewhere

VITAMIN D STATUS IN HOSPITALIZED PATIENTS WITH SARS-CoV-2 INFECTION

The Journal of Clinical Endocrinology & Metabolism, dgaa733, https://doi.org/10.1210/clinem/dgaa733

Jose L. Hernandez1'10, Daniel Nan1,10, Marta Fernandez-Ayala1, Mayte Garcfa-Unzueta2, Miguel A. Hernandez-Hernandez3, Marcos Lopez-Hoyos4, Pedro Munoz Cacho5, Jose M. Oimos1-10, Manuel Gutierrez-Cuadra6, Juan J. Ruiz-Cubillan7, Javier Crespo8,10, Victor M. Martfnez-Taboada9,10

Background: The role of vitamin D status in COVID-19 patients is a matter of debate.

Objectives: To assess serum 25-hydroxyvitamin D (25OHD) levels in hospitalized patients with COVID-19 and to analyze the possible influence of vitamin D status on disease severity.

Methods: Retrospective case-control study of 216 COVID-19 patients and 197 population-based controls.

Serum 25OHD levels were measured in both groups. Besi COVID-19 severity (admission to the Intensive Care Unit, re was also evaluated.

Results: Of the 216 patients, 19 were on vitamin D s patients, mean±SD25〇Hd levels were 13.8±7.2ng/ml，compared to 20.9±7.4ng/ml in controls (p<0.0001). 25OHD values were lower in men than in women. Vitamin D deficiency was found in 82.2% of COVID-19 cases and 47.2% of population-based controls (p<0.0001). 25OHD inversely correlate to serum ferritin (p=0.013) and D-dimer levels (p=0.027). Vitamin D-deficient COVID-19 patients had a greater prevalence of hypertension and cardiovascular diseases, raised serum ferritin and troponin levels, as well as a longer length of hospital stay than those with serum 25OHD levels >20 ng/ml. No causal relationship was found between vitamin D deficiency and COVID-19 severity as a combined endpoint or as its separate components.

Conclusions: 25OHD levels are lower in hospitalized COVID-19 patients compared to population-based controls and these patients had a higher prevalence of deficiency. We did not find any relationship between vitamin D concentrations or vitamin deficiency and the severity of the disease.

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