ADHD significantly treated by daily Magnesium plus weekly Vitamin D – RCT
The effect of vitamin D and magnesium supplementation on the mental health status of attention-deficit hyperactive children: a randomized controlled trial
BMC Pediatrics volume 21, Article number: 178 (2021)
Mostafa Hemamy, Naseh Pahlavani, Alireza Amanollahi, Sheikh Mohammed Shriful Islam, Jenna McVicar, Gholamreza Askari & Mahsa Malekahmadi
Background
Attention-Deficit / Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, characterized by varying severity in attention deficit and hyperactivity. Studies have shown deficiencies in the serum level of magnesium and vitamin D in people with ADHD. The aim of this study is to determine the effect of vitamin D and magnesium supplementation on mental health in children with ADHD.
Methods
We conducted a randomized, double blind, placebo-controlled clinical trial of 66 children with ADHD. Participants were randomly allocated to receive both vitamin D (50,000 IU/week) plus magnesium (6 mg/kg/day) supplements (n = 33) or placebos (n = 33) for 8-weeks. Strengths and difficulties questionnaire was used to evaluate children’s mental health at baseline and the end of the study.
Results
After eight weeks of intervention, the serum levels of 25-hydroxy-vitamin D3 and magnesium increased significantly in the intervention group compared with the control group. Also, children receiving vitamin D plus magnesium showed a significant reduction in
emotional problems (p = 0.001),
conduct problems (p = 0.002),
peer problems (p = 0.001),
prosocial score (p = 0.007),
total difficulties (p = 0.001),
externalizing score (p = 0.001), and
internalizing score (p = 0.001)
compared with children treated with the placebo.
Conclusion
Vitamin D (50,000 IU/week) and magnesium (6 mg/kg/day) co-supplementation for a duration of 8-weeks could improve the behavioral function and mental health of children with ADHD. However, further well-designed studies with a larger sample size are needed.
📄 Download the PDF from VitaminDWiki
VitaminDWiki - studies in both categories ADHD and Magnesium
This list is automatically updated
{category}
ADHD and Vitamin D Deficiency category contains (as of Nov 2022)
ADHD and Vitamin D Deficiency category listing has items
ADHD = Attention Deficit Hyperactivity Disorder Wikipedia
ADHD children have much lower levels of vitamin D
ADHD is more likely if low vitamin D in early pregnancy
Less sun is associated with more ADHD (season and latitude)
The ADHD rate has increased a lot in past few decades - especially for adults
Vitamin D levels have dropped a lot in the past few decades
There are many positive observational studies of Vitamin D and ADHD
ADHD shares risk factors with Autism and many other diseases
- Low Vitamin D, Low Omega-3, Low Magnesium, Low UVB (= high latitude or winter)
Magnesium and mental illness chart
Which is in Overview Magnesium and vitamin D