2.9 X less risk of COVID ICU if seniors had supplemented with Vitamin D (any amount)
Vitamin D and COVID-19 Severity in Hospitalized Older Patients -Potential Benefit of Prehospital Vitamin D Supplementation
François Parant 1, Justin Bouloy 2,* , Julie Haesebaert 3,4 , Lamia Bendim’red 5, Karine Goldet 5,
Philippe Vanhems 6,7, Laetitia Henaff 6,7, Thomas Gilbert 2,4 , Charlotte Cuerq 1, Emilie Blond 1, Muriel Bost 1
and Marc Bonnefoy 2
ICU Average for any dosing interval: 1,000 IU daily up to 100,000 IU very 3 months
Studies involving the associations between vitamin D supplementation taken before the onset of COVID-19 infection and the clinical outcomes are still scarce and this issue remains controversial. This study aimed to assess the relationships between vitamin D (VitD) status and supplementation and coronavirus disease 2019 (COVID-19) severity in older adults (average age of 78 years) hospitalized for COVID-19. We conducted an observational retrospective cohort study with 228 older hospitalized patients during the first wave of the COVID-19 pandemic. The outcomes were in-hospital mortality secondary to COVID-19 or critically severe COVID-19. A logistic regression analysis was conducted to test whether pre-hospital VitD supplementation was independently associated with severity. In this study, 46% of patients developed a severe form and the overall in-hospital mortality was 15%.
Sixty-six (29%) patients received a VitD supplement during the 3 months preceding the infection onset. Additionally, a VitD supplement was associated with fewer severe COVID-19 forms (OR = 0.426, p = 0.0135) and intensive care unit (ICU) admissions (OR = 0.341, p = 0.0076). As expected, age > 70 years, male gender and BMI ≥ 35 kg/m2 were independent risk factors for severe forms of COVID-19. No relationship between serum 25(OH)D levels and the severity of the COVID-19 was identified. VitD supplementation taken during the 3 months preceding the infection onset may have a protective effect on the development of severe COVID-19 forms in older adults. Randomized controlled trials and large-scale cohort studies are necessary to strengthen this observation.
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Study Observations by VitaminDWiki
Study is based on data from early 2020.
- Wonder why they took so long to publish it?
Study only reports on those seniors who went to the hospital.
Suspect that many seniors who supplemented never went to the hospital.
Study did not compute ICU risk vs dose size nor dose interval
- which ranged from as much as 80,000 IU every 3 months to as little as 1,000 IU daily.
Vitamin D levels measured in the hospital were not statistically significantly related to any COVID variable
Vitamin D may not have been the reason for the benefit. Might have just tried many ways to improve health.
- Other possible reasons include: take Magnesium, take Omega-3, take Vitamin K2, eat better, exercise more
VitaminDWiki – COVID-19 treated by Vitamin D - studies, reports, videos
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