Association of vitamin D intake and serum levels with fertility: results from the Lifestyle and Fertility Study
Fertility and Sterility, Available online 16 June 2017
June L. Fung, Ph.D.a, , , Terryl J. Hartman, Ph.D.b, Rosemary L. Schleicher, Ph.D.c, Marlene B. Goldman, Sc.D.a, d
a Department of Obstetrics and Gynecology, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire
b Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia
c Division of Laboratory Sciences, National Center for Environmental Health, Centers for ,Disease Control and Prevention, Atlanta, Georgia
d Community and Family Medicine, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire
If they had considered good male vitamin D levels there would have been about double the benefits
- Male fertility 4 X higher if high Vitamin D – Nov 2015
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
Fertility and Sperm category contains
see also Overview Women and Vitamin D
Overview Pregnancy and vitamin D Fertility and Vitamin D – several articles
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Conception and vitamin D snapshot as of 2012
Objective: To evaluate the role of vitamin D intake and serum levels on conception of clinical pregnancy and live birth.
Design: Prospective cohort study.
Setting: Academic medical centers.
Patient(s): Healthy, nulliparous women, age 18–39 years, and their male partners.
Main Outcome Measure(s): Clinical pregnancy and live birth were compared between those who did or did not meet the vitamin D estimated average requirement (EAR) intake (10 μg/d) and with serum 25-hydroxyvitamin D (25(OH)D) considered at risk for inadequacy or deficiency (<50 nmol/L) or sufficient (≥50 nmol/L).
Result(s): Among 132 women, 37.1% did not meet the vitamin D EAR and 13.9% had serum levels at risk for inadequacy or deficiency.
Clinical pregnancies were significantly higher among women who met the vitamin D EAR (67.5% vs. 49.0%) and with sufficient serum 25(OH)D (64.3% vs. 38.9%) compared with those who did not.
Live births were higher among those who met the vitamin D EAR (59.0% vs. 40.0%). The adjusted odds ratio (AOR) of conceiving a clinical pregnancy was significantly higher among those who met the EAR (AOR = 2.26; 95% confidence interval CI, 1.05–4.86) and had sufficient serum 25(OH)D (AOR = 3.37; 95% CI, 1.06–10.70). The associations were not significant after controlling for selected nutrients and dietary quality.
Conclusion(s): Women with vitamin D intake below EAR and serum 25(OH)D levels at risk for inadequacy or deficiency may be less likely to conceive and might benefit from increased vitamin D intake to achieve adequacy.
Clinical Trial Registration Number: NCT00642590.
Available online 16 June 2017 https://doi.org/10.1016/j.fertnstert.2017.05.037 Purchase $35.95
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