The vitamin D receptor: contemporary genomic approaches reveal new basic and translational insights
J Clin Invest. First published February 27, 2017 doi:10.1172/JCI88887.
J. Wesley Pike, Mark B. Meyer, Seong-Min Lee, Melda Onal, and Nancy A. Benkusky
Vitamin D Receptor category has the following
Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells
A poor VDR increases the risk of 29+ health problems click here for details
VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR
You can compensate for poor VDR by increasing one or more of the following:
|1) Vitamin D supplement|
Sun, Ultraviolet -B
| Vitamin D in the blood |
and thus to the cells
|2) Magnesium||Vitamin D in the blood |
AND to the cells
|3) Omega-3||Vitamin D to the cells|
|4) Resveratrol||Vitamin D to the cells|
|5) Intense exercise||Vitamin D Receptor|
|6) Get prescription for VDR activator|
|Vitamin D Receptor|
|7) Quercetin (flavonoid)||Vitamin D Receptor|
|9.6||Chronic Periodontitis |
|5.8||Low back pain in athletes|
|5||Coronary Artery Disease|
|3.1||Lumbar Disc Degeneration|
|2.8||Osteoporosis if COPD|
|1.6||Type I Diabetes|
|1.6||Prostate Cancer while black|
|1.5||Type II Diabetes|
The vitamin D receptor (VDR) is the single known regulatory mediator of hormonal 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] in higher vertebrates.
It acts in the nucleus of vitamin D target cells to regulate the expression of genes whose products control diverse, cell type–specific biological functions that include mineral homeostasis.
In this Review we describe progress that has been made in
- defining new cellular sites of action of this receptor,
- the mechanisms through which this mediator controls the expression of genes,
- the biology that ensues, and the
- translational impact of this receptor on human health and disease.
We conclude with a brief discussion of what comes next in understanding vitamin D biology and the mechanisms that underlie its actions.
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