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Prostate cancer in black men is 1.6 times more likely if a poor Vitamin D Receptor – Feb 2017

Association of VDR polymorphisms ( Taq I and Bsm I) with prostate cancer: a new meta-analysis.

J Int Med Res. 2017 Feb;45(1):3-10. doi: 10.1177/0300060516668939. Epub 2017 Jan 17.
Liu S1, Cai H1, Cheng W1, Zhang H1, Pan Z1, Wang D2.
1 Department of Urology Surgery, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
2 Department of Clinical Laboratory Medicine, Taizhou University Affiliated Taizhou Municipal Hospital, Taizhou, China.
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VitaminDWiki

Items in both categories Prostate Cancer and Dark Skin are listed here:

Vitamin D Receptor category has the following

186 items in Vitamin D Receptor category

Vitamin D tests cannot detect Vitamin D Receptor (VDR) problems
A poor VDR restricts Vitamin D from getting in the cells

A poor VDR increases the risk of 37 health problems  click here for details

VDR at-home test $29 - results not easily understood in 2016
There are hints that you may have inherited a poor VDR
You can compensate for poor VDR by increasing one or more of the following:

IncreasingIncreases
1) Vitamin D supplement
  Sun, Ultraviolet -B
Vitamin D in the blood
and thus to the cells
2) MagnesiumVitamin D in the blood
 AND to the cells
3) Omega-3 Vitamin D to the cells
4) Resveratrol Vitamin D to the cells
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor


See chart at the bottom of VDR page for Magnesium, Omega-3 and Resveratrol

If poor Vitamin D Receptor

Risk
increase
Health Problem
13Sepsis
9.6Chronic Periodontitis
   and smoke
7.6Crohn's disease
5.8Low back pain in athletes
5Ulcerative Colitis
5Coronary Artery Disease
4.6Breast Cancer
4polycystic ovary syndrome
3.3 Pre-term birth
3.1Lumbar Disc Degeneration
3.1Colon Cancer survival
3 Multiple Sclerosis
3Dengue
3 Waist size
3 Ischemic Stroke
3Alzheimer’s
2.8Osteoporosis
2.7Gastric Cancer
2.6Lupus in children
2.4Lung Cancer
2.3Autism
2Diabetic Retinopathy
2Parkinson's
2 Wheezing/Asthma
2 Melanoma   Non-melanoma Skin Cancers
2Myopia
1.9Uterine Fibroids
1.9Early tooth decay
1.8Diabetic nephropathy
1.6Diabetes - Type I
1.6Prostate Cancer while black
1.5 Diabetes -Type II
1.5Pertusus
1.4 Rheumatoid arthritis
1.3Childhood asthma
1.3Tuberculosis

FREE PDF is online

Objective Prostate cancer is a malignant tumour that poses a serious risk to human health. Epidemiological studies suggest that it may be associated with vitamin D receptor gene ( VDR) polymorphisms. Previous work investigated potential risks between Taq I (rs731236) and Bsm I (rs1544410) VDR polymorphisms with prostate cancer in humans; however, results are inconsistent.

Methods We conducted a meta-analysis to retrieve genetic association analyses of rs731236 and rs1544410 polymorphisms with prostate cancer from studies published between 2006-2016. Pooled odds ratios with 95% confidence intervals were used to assess genetic associations, and heterogeneity was assessed by Q and I2 statistics.

Results Our findings suggest a significant association between rs731236 and prostate cancer risk in Asians and African Americans, but rs1544410 was not associated with prostate cancer under three genetic models.

Conclusion Future studies including larger sample sizes and the analysis of gene functions are needed to help develop prostate cancer treatment.

PMID: 28222630 DOI: 10.1177/0300060516668939

Attached files

ID Name Comment Uploaded Size Downloads
7806 A-A prostate.jpg admin 06 Mar, 2017 23:12 37.13 Kb 90
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