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Pre-eclampsia is not reduced by vitamin D (if you ignore vitamin D level, dose size, frequency and duration) – July 2017

The role of vitamin D in pre-eclampsia: a systematic review.

BMC Pregnancy Childbirth. 2017 Jul 15;17(1):231. doi: 10.1186/s12884-017-1408-3.

VitaminDWiki

Pages listed in BOTH the VitaminDWiki categories
    Pregnancy & Hypertension (preeclampsia)


Vitamin D charts from GrassrootsHealth - May 2016 has the following chart

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Purswani JM1, Gala P2, Dwarkanath P3, Larkin HM1, Kurpad A3, Mehta S4,5.
1 Division of Nutritional Sciences, Cornell University, 314 Savage Hall, Ithaca, NY, 14853, USA.
2 Weill-Cornell Medical College, New York, NY, USA.
3 St. John's Research Institute, Bangalore, Karnataka, India.
4 Division of Nutritional Sciences, Cornell University, 314 Savage Hall, Ithaca, NY, 14853, USA. smehta at cornell.edu.
5 St. John's Research Institute, Bangalore, Karnataka, India. smehta at cornell.edu.

BACKGROUND:
The etiology of pre-eclampsia (PE) is not yet fully understood, though current literature indicates an upregulation of inflammatory mediators produced by the placenta as a potential causal mechanism. Vitamin D is known to have anti-inflammatory properties and there is evidence of an inverse relationship between dietary calcium intake and the incidence of PE. Evidence of the role of vitamin D status and supplementation in the etiology and prevention of PE is reviewed in this article along with identification of research gaps to inform future studies.

METHODS:
We conducted a structured literature search using MEDLINE electronic databases to identify published studies until February 2015. These sources were retrieved, collected, indexed, and assessed for availability of pregnancy-related data on PE and vitamin D.

RESULTS:
Several case-control studies and cross-sectional studies have shown an association between vitamin D status and PE, although evidence has been inconsistent. Clinical trials to date have been unable to show an independent effect of vitamin D supplementation in preventing PE.

CONCLUSIONS:
The included clinical trials do not show an independent effect of vitamin D supplementation in preventing PE; however, issues with dose, timing, and duration of supplementation have not been completely addressed.

PMID: 28709403 DOI: 10.1186/s12884-017-1408-3

Created by admin. Last Modification: Monday July 17, 2017 10:02:14 UTC by admin. (Version 3)

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