Role of Vitamin D in the Development of Obesity
Int. J. Morphol,. 35(4):1568-1575, 2017.
Merino, O.1,2; Gregorio, B.3; Sampaio, F.3; Sanchez, R.1’4 & Risopatron, J.1’5
Least weight gain = Vitamin D + low fat diet
Most weight gain = No Vitamin D + high fat diet
- Dieters lost 5 more pounds if achieved more than 32 ng of vitamin D – RCT March 2014
- Obesity epidemic: a perfect storm of deficiency of vitamin D, Magnesium, Iodine, etc – May 2012
- Less weight gain if add Vitamin D, even if have a high fat diet (in rats) – RCT Dec 2017
- Overweight and obese lost 12 lbs with vitamin D in 6 months– RCT May 2015
Overview Obesity and Vitamin D contains the following summary
- FACT: People who are obese have less vitamin D in their blood
- FACT: Obese need a higher dose of vitamin D to get to the same level of vit D
- FACT: When obese people lose weight the vitamin D level in their blood increases
- FACT: Adding Calcium, perhaps in the form of fortified milk, often reduces weight
- FACT: 126 trials for vitamin D intervention of obesity as of Dec 2017
- FACT: Less weight gain by senior women with > 30 ng of vitamin D
- FACT: Dieters lost additional 5 lbs if vitamin D supplementation got them above 32 ng - RCT
- FACT: Those with darker skins were more likely to be obese Sept 2014
- SUGGESTION: Probably need more than 4,000 IU to lose weight if very low on vitamin D due to
risk factors such as overweight, age, dark skin, live far from equator,shut-in, etc.
- Obesity category has
Antecedents in the literature suggest that vitamin D (VD) play a role in overweigh/obesity. The present study evaluated the effect of VD deficiency diet intake and fat hight on overweight/obesity about white adipose tissue (WAT) and body mass (BM) gain. Animals were divided into four experimental groups according to the lipid and VD content of their diets; G1: CVD+ (C: control diet with VD+; n=5), G2: CVD- (control diet without VD-; n=5), G3: HFVD+ (high fat diet, with VD+; n=5), G4: HFVD- (HF diet without VD-; n=5). The diets were administered for three months and BW was monitored weekly. At the end of this period all animals were euthanized. Epididymal (EFM), retroperitoneal (RFM) and subcutaneous (SFM) fat mass were removed, weighted. At 12 weeks the body mass of the animals that were fed without VD- diets; G2: 507.60+17.31 g, and G4: 528.50+13.50 g were significantly higher (p < 0.05), than the counterparts G1: 485.0+11.29 g and G3: 521.20+26.20 g respectively. Similarly, the animals fed with VD- diets had a greater EFM and SFM (p < 0.05) compared with the respective controls (VD+). Nevertheless, the animals fed with high fat diet had equal RFM (G3: 12.2+4.10 g, G4: 12.88+2.3 g, p > 0.05). The results demonstrate that the nutrition of rats with diet deficient in VD and high fat, promotes overweight by increasing fat deposits, suggestion a cause-effect relationship between VD deficiency and overweight. These results suggest that VD deficiency increases the risk of visceral fat obesity in males.
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