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Hypertension risk decreased 10X by increasing vitamin D levels to more than 40 ng – Nov 2017

The Association between Serum 25(OH)D Status and Blood Pressure in Participants of a Community-Based Program Taking Vitamin D Supplements

Nutrients 2017, 9(11), 1244; doi:10.3390/nu9111244
Naghmeh Mirhosseini 1, Hassanali Vatanparast 2, and Samantha M. Kimball 1,*
1 Pure North S’Energy Foundation, Calgary, AB T2R 0C5, Canada
2 College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK S7N 5C9, Canada


 Download the PDF from VitaminDWiki

Background: Vitamin D deficiency is a risk factor for hypertension.

Methods: We assessed 8155 participants in a community-based program to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) status and blood pressure (BP) and the influence of vitamin D supplementation on hypertension. Participants were provided vitamin D supplements to reach a target serum 25(OH)D > 100 nmol/L. A nested case-control study was conducted to examine the effect of achieving physiological vitamin D status in those who were hypertensive and not taking BP-lowering medication, and hypertensive participants that initiated BP-lowering medication after program entry.

Results: At baseline, 592 participants (7.3%) were hypertensive; of those, 71% were no longer hypertensive at follow-up (12 ± 3 months later). There was a significant negative association between BP and serum 25(OH)D level (systolic BP: coefficient = −0.07, p < 0.001; diastolic BP: coefficient = −0.1, p < 0.001). Reduced mean systolic (−18 vs. −14 mmHg) and diastolic (−12 vs. −12 mmHg) BP, pulse pressure (−5 vs. −1 mmHg) and mean arterial pressure (−14 vs. −13 mmHg) were not significantly different between hypertensive participants who did and did not take BP-lowering medication.

Conclusion: Improved serum 25(OH)D concentrations in hypertensive individuals who were vitamin D insufficient were associated with improved control of systolic and diastolic BP.

Clipped from PDF
“After correcting for probable confounding factors. . . only those participants that were vitamin D insufficient at baseline that achieved optimal serum 25(OH)D status at follow-up (≥100 nmol/L) had a lower risk of hypertension (OR = 0.10, 95% CI: 0.01, 0.87, p = 0.03).”


Interesting to see the improved health vs vitamin D levels BEFORE the addition of vitamin D

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Created by admin. Last Modification: Sunday November 19, 2017 16:28:13 UTC by admin. (Version 4)

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8764 Baseline.jpg admin 19 Nov, 2017 16:12 123.15 Kb 25
8763 Hypertesion 40 ng.pdf PDF 2017 admin 19 Nov, 2017 16:12 423.86 Kb 16
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