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Diabetes risk reduced 35 percent when adult Vitamin D levels are kept high – Nov 2017

Both youth and long-term vitamin D status is associated with risk of type 2 diabetes mellitus in adulthood: a cohort study

J Annals of Medicine, online: 07 Nov 2017, http://dx.doi.org/10.1080/07853890.2017.1399446
Feitong Wu ORCID Icon, Markus Juonala, Niina Pitkänen, Antti Jula, Terho Lehtimäki, Matthew

VitaminDWiki

Overview Diabetes and vitamin D contains the following summary

  • Diabetes is 5X more frequent far from the equator
  • Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
  • Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
  • Sedentary people get less sun / Vitamin D
  • Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
  • Elderly get 4X less vitamin D from the same amount of sun
        Elderly also spend less time outdoors and have more clothes on
  • All items in category Diabetes and Vitamin D 339 items: both Type 1 and Type 2

Vitamin D appears to both prevent and treat diabetes

  • Appears that >2,000 IU will Prevent
  • Appears that >4,000 IU will Treat , but not cure
  • Appears that Calcium and Magnesium are needed for both Prevention and Treatment
        which are just some of the vitamin D cofactors

Diabetes category starts with the following

339 items In Diabetes category

see also Overview Diabetes and vitamin D  Overview Metabolic Syndrome and vitamin D

Autoimmune category listing has 102 items along with related searches

T1 diabetes OR type1 diabetes in title 102 as of June 2017
prediabetes OR prediabetic 212 items as of Dec 2016
Search VitaminDWiki for Peripheral Neuropathy 107 items June 2017

Most visited 10 pages in Diabetes category

Id Page Hits Last modification Creator Categories
5526 Gestational Diabetes reduced with 50,000 IU of vitamin D every 3 weeks and daily Calcium – RCT June 2014 112142
20 Jul, 2017 14:22
admin Pregnancy
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Intervention
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Intervention - non daily
339 Overview Diabetes and vitamin D 59155
05 Nov, 2017 22:16
admin Diabetes
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3405 Diabetes 28978
09 Nov, 2017 12:36
ricks99 Diabetes
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720 Overview Metabolic Syndrome and vitamin D 22395
26 Oct, 2016 13:07
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62 Vitamin D decreases incidence of disease 20501
13 Sep, 2017 23:34
admin How much Vitamin D
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Rickets
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About D - introduction
Cancer
1761 Diabetes rising quickly in areas with recent air conditioning – June 2011 10689
26 Jul, 2013 19:37
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5323 Gestational Diabetes reduced 40 percent by 5,000 IU of vitamin D – RCT April 2014 9313
03 Sep, 2016 15:36
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3800 Diabetic Neuropathy sometimes can be reversed by vitamin D 8890
29 Sep, 2017 00:15
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5243 Blood pressure in diabetics reduced by 12 weekly doses of 50,000 IU vitamin D – RCT Jan 2014 8593
20 Jul, 2017 17:33
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Intervention - non daily
1294 Can Vitamin D treat Diabetes - many articles 7925
13 Sep, 2014 01:40
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Treatment by Vitamin D


Key Messages

  • High serum 25OHD levels in youth, and between youth and adulthood, were associated with a lower risk of T2DM in adulthood.
  • Each SD (15.2 nmol/L) increment in youth serum 25OHD levels was associated with a 26% reduction in odds for T2DM, which was independent of a number of confounding variables and other risk factors for T2DM. A similar magnitude of association was observed for the long-term 25OHD levels between youth and adulthood.
  • These findings suggest a potentially simple and cost-effective strategy for reducing adulthood risk of T2DM starting in an earlier stage of life – improving and maintaining vitamin D status throughout youth and early adulthood.

Objectives: To determine whether vitamin D status in childhood and adolescence (herein collectively referred to as youth) and the long-term status from youth to adulthood is associated with risk of developing type 2 diabetes mellitus (T2DM) and impaired fasting glucose (IFG) in adulthood.

Materials and methods: This was a 31-year follow-up study of 2300 participants aged 3–18 years. Multinomial logistic regression was used to assess the association of both (a) baseline 25-hydroxyvitamin D (25OHD) levels and (b) the mean of baseline and the latest follow-up 25OHD levels (continuous variable and quartiles) with incident T2DM and IFG (cut-off = 5.6 mmol/L) in adult life.

Results: High serum 25OHD levels in youth and also mean values from youth to adulthood were associated with reduced risk of developing T2DM in adulthood (odds ratio, 95% confidence interval= 0.73, 0.57–0.95 and 0.65, 0.51–0.84, respectively, for each SD increment in 25OHD). Compared to Q1, a dose-dependent negative association was observed across other quartiles of youth 25OHD, while the strongest association was found in the Q3 for the mean 25OHD levels. Neither youth nor the mean 25OHD was associated with IFG.

Conclusions: High serum 25OHD levels in youth, and from child to adult life, were associated with a reduced risk of developing T2DM in adulthood.

Publisher wants $54 for the PDF

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