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947,000 people in the US had Multiple Sclerosis 2008-2010 – Nov 2017

Nearly 1 Million Americans Have Multiple Sclerosis, NMSS Prevalence Study Finds

  • “An estimated 947,000 people in the U.S. have multiple sclerosis (MS) — more than double the long-accepted figure of 400,000 — according to a newly completed study organized and funded by the National Multiple Sclerosis Society (NMSS).”

Poster was presented at international MS conference in France

  • $1 million study for working group of 15 to 20 epidemiologists, statisticians and neurologists meeting virtually every week
  • “Collectively, these six databases provided information on more than 100 million people — or well over a third of the U.S. population — with the rationale that “nearly all persons with MS, except the uninsured, would be captured in one of these programs.””
  • Among its limitations, the NMSS study excludes children, Native Americans, undocumented residents and prisoners, as well as people who seek treatment at alternative medical clinics rather than the healthcare insurance system.” [undercount]
  • The study showed an overall MS prevalence of 402.8 cases per 100,000 inhabitants — up from 58 per 100,000 in 1976 and 85 per 100,000 for the period 1989-94.
  • “Interestingly, the NMSS study doesn’t look at incidence — the number of new cases that appear in any given year — but rather prevalence. Nor does it break down prevalence according to type of MS”

The Prevalence of Multiple Sclerosis in the United States: A Population-Based Healthcare Database Approach

ECTRIMS Online Library. Wallin M. Oct 26, 2017

Background: Within the US, the prevalence of multiple sclerosis (MS) is poorly understood and inadequately characterized, but such information is important to support planning of health services and advocacy efforts. We aimed to develop a case definition to identify people with MS using health claims databases, and to apply this definition across the US to generate robust population-based MS prevalence estimates.

Methods: An MS case definition was developed and validated in three independent administrative databases. We applied this definition to identify MS cases between 2008 and 2010 using the following health care databases:

  • Optum,
  • Truven,
  • Department of Veterans Affairs (VA),
  • Kaiser Permanente Southern California (KPSC),
  • Medicare and Medicaid.

We estimated the three-year cumulative prevalence, and standardized to the 2010 US population.

Results: Among individuals with at least one health claim for demyelinating disease, the case definition had a sensitivity of 86%, specificity: 76-82%, and positive predictive value: 96-98% when compared to physician-adjudicated diagnoses.
The unadjusted cumulative prevalence of MS for 2008-2010 for the private insurance databases was

  • 208 per 100,000 (95% CI: 205-211) for Optum and
  • 208 per 100,000 (95% CI: 207-210) for Truven.

The cumulative prevalence for the

  • national VA health care system was 177 per 100,000 (95% CI: 174-181), and for
  • KPSC was 110 per 100,000 (95% CI: 106-114).

The female: male ratio for MS prevalence was about 3:1 across databases and a US geographic prevalence gradient was found. A final integrated national MS cumulative prevalence estimate will be generated and stratified by age, sex and geographic region.

Conclusion: The US national cumulative MS prevalence rates for 2008-10 are the highest reported to date and provide a contemporary understanding of the disease burden. Our rigorous algorithm-based approach to estimating prevalence is novel, efficient and has the potential to be used for other chronic conditions.


See also VitaminDWiki

Overview MS and vitamin D contains the following summary

Clinical interventions have shown that Vitamin D can prevent, treat, and even cure Multiple Sclerosis, at a tiny fraction of the cost of the drugs now used to treat it, and without side effects.

Summary: lack of consensus on how much to prevent, treat, or cure MS

  • How much Vitamin D to prevent many diseases - such as MS
  • How much Vitamin D is needed to treat MS? There is currently no agreement
       The recommendations range from 40 to 100 ng - which can result of a dose ranging from 3,000 to 20,000 IU/day
  • How Vitamin D is needed to Cure MS?: It appears that 20,000-140,000 IU daily may be needed to CURE the disease
       You must be under the supervision of a doctor who knows what to watch for in your individual situation.
       High doses of Vitamin D cannot be used as a monotherapy.
       You will need to adjust the cofactors: Typically increasing Magnesium and Vitamin K2, and reducing Calcium intake.
       Your doctor will monitor these and might increase your intake of Vitamins B2, C, as well as Omega-3

Multiple Sclerosis and (lots of) Vitamin D - book by patient on Coimbra protocol - Feb 2016 contains protocol description

Vitamin D Protocol used by Dr. Coimbra for Multiple Sclerosis etc.
Snips as of April 2016 http://www.vitamindprotocol.com/dr.-coimbra-s-ms-protocol.html

  • 1,000 IU's vitamin D per kilogram as a first approximation
    (apparently increased/decreased depending of resulting vitamin D blood level)
  • Vitamin B2, magnesium glycinate, boron, chromium picolinate, Omega 3 DHA, Zinc, Methylcobalamin form of B12, Choline, etc.
  • Lack of B12 may affect 10%–15% of the general population and may be the most prevalent genetic risk factor for several human diseases
  • Discontinue eating or drinking dairy products or calcium enriched foods or beverages, also no Ca supplements
  • Drink as least 2.5 liters [85 ounces] of fluids, preferably water
  • Required Tests:​ Vitamin D, Parathyroid, Blood calcium, urinary calcium

Multiple Sclerosis and (lots of) Vitamin D - book by patient on Coimbra protocol - Feb 2016 contains Facebook Groups

Facebook pages on Vitamin D and Multiple Sclerosis (original list)

From list on Google Drives
English

Brazilian/Portuguese

German

Spanish

French

Italian

Romanian

Greek

Western Balkan countries, Croatia and Slovenia 7,000 members at end of March 2017

Slovene

Macedonian

Lithuanian

Norwegian

Serbian:

Russian added Feb 2017

Some Facebook pages on just Vitamin D

Created by admin. Last Modification: Tuesday November 21, 2017 01:24:01 UTC by admin. (Version 2)
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