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Overview Pregnancy and vitamin D

Vitamin D before, during, and after pregnancy   =alternate name

The more vitamin D for mom, the more benefits for both of them

  • The benefits to mom start about 2,000 IU daily average (2000 IU costs less than $15 per year)
  • Substantial benefits proven for 4,000 IU taken during pregnancy (fewer complications, lower cost)
  • Best benefits at 6,000 IU - this much is also needed if breast feeding without supplementing the infant
  • Taking > 2,000 IU raises the cost, primarily due to cost of Cofactors.

Vitamin D during pregnancy

IU Cumulative Benefit Blood level CofactorsCalcium $*/month
200 Better bones for mom
with 600 mg of Calcium
6 ng/ml increase Not needed No effect $0.10
400 Less Rickets (but not zero with 400 IU)
3X less adolescent Schizophrenia
Fewer child seizures
20-30 ng/ml Not needed No effect $0.20
2000 2X More likely to get pregnant naturally/IVF
2X Fewer dental problems with pregnancy
8X less diabetes
4X fewer C-sections (>37 ng)
4X less preeclampsia (40 ng vs 10 ng)
5X less child asthma
2X fewer language problems age 5
42 ng/ml Desirable < 750 mg $1
4000 2X fewer pregnancy complications
2X fewer pre-term births
49 ng/ml Should have
cofactors
< 750 mg $3
6000 Probable: larger benefits for above items
Just enough D for breastfed infant
More maternal and infant weight
Should have
cofactors
< 750 mg $4

$* assumes

  • You buy fairly |low cost vitamin D and Cofactors (more expensive if liquid and/or vegan )
  • Using a low cost size of vitamin D - such as 5,000 IU, as often as needed. (50,000 IU costs even less)
    Example: 5000 IU every other day if you only want an average of 2500 IU
  • Test vitamin D levels of only those moms who are at high risk for being vitamin D deficient
       $30 for a blood test about 6 weeks after starting vitamin D to check that high-risk mom is getting enough

Benefits which do not fit into the previous matrix

Pregnancy - general

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Preterm and low weight births

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Increased pre-term birth if black or if high UV index (stay inside - away from the hot sun)

PubMed:  24618066 April 2014

IU for infants

Low Levels among mothers and infants

see wikipage: http://www.vitamindwiki.com/tiki-index.php?page_id=2563

Preeclampsia

Infants

20X more than US standard - Wagner April 2010 slide 31
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Chart by Heaney,  downloaded from Grassroots April 2010 – video expected June
Fewer than 40% of infants got 400 IU of vitamin D, The amount recommended by American Academy of Pediatrics

A June 2010 study which includes the following graph, found that MANY children do not even get 200 IU

and NONE of the children got more than 480 IU

from Dietary Guidelines for Americans vitamin D - June 2010

Note: When infant stops drinking vitamin D fortified milk, be sure to supplement with vitamin D - as most fruit juice is not fortified.

Rickets/Battered Child/Weak bones

High risk of being vitamin D deficient during pregnancy

Potential high risk if : dark skin, twins, recent pregnancy, smoking, very far from equator, obese, excessive clothes,

BEFORE: Help getting pregnant - woman & man

Vitamin D increases fertility of BOTH the woman.and the man
Each 1 ng increase in blood level of vitamin D increases clinical pregnancy by 6%
You may not have heard much about it since it has been patented
   see also Who said vitamin D could not be patented
Vitamin D has been used by zoos and vets for a long time to increase fertility


Decrease in C sections as vitamin D levels are increased

C-section 4X more likely if less than 20 ng of vitamin D – May 2012
Risk of Cesarean 2X higher if low vitamin D – April 2012
C-section 4X more likely when vitamin D less than 37 ng – many items
Search VitaminDWiki for cesarean 90 items as of Aug 2014


The articles in both of the categories Pregnancy AND Depression are here:


New York Times on Postpartum depression June 2014. No mention of Vitamin D


See also VitaminDWiki

6400 IU of vitamin D got mothers to 50+ nanograms

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See also web

  • Clinical Trials for Pregnacy with vitamin D INTERVENTION 38 as of Aug 2014
  • Pharmacokinetics of a single oral dose of vitamin D3 (70,000 IU) in pregnant and non-pregnant women Dec 2012
    PDF is attached at the bottom of this page
  • Vitamin D Supplementation During Pregnancy: Is It Necessary? Medscape Sept 2013
    Nope maternal 25(OH)D levels in any trimester failed to significantly affect the bone-mineral content of offspring
    They fail to consider anything other than bone content at age 10!!
  • Google Sites on Vitamin D and pregnancy Oct 2013 included links to the following
    Vitamin D may be useful as immunotherapy in treatment of recurrent miscarriage
    Vitamin D reduces inflammation associated with miscarriage
    4000 IU Vitamin D daily lowers rates of infection, preterm labor and preterm birth
    Vitamin D required for fetal development; deficiency causes preeclampsia, gestational diabetes
    Vitamin D levels not associated with fertility or pregnancy outcome except late miscarriage
    Plasma vitamin D concentrations may affect pregnancy outcomes.
    Low vitamin D leads to failed IVF attempts
    Having sufficient vitamin D levels is associated with 4 times higher success rate in IVF
    93% of infertile women were low in vitamin D
    High or low vitamin D associated with lower sperm count, motility and morphology
    High vitamin D levels associated with higher sperm motility and morphology
    Extra vitamin D increases litter size in pigs and has a trend towards higher pregnancy rates
    Vitamin D deficiency leads to fewer offspring in mice
    Vitamin D deficiency impairs egg production, elevates LH and FSH
    Vitamin D stimulates estrogen and progesterone production by the placenta
    Vitamin D stimulates progesterone and estrogen production in the ovary
    Excess Vitamin D reduces the function of the corpus luteum and decreases progesterone
  • Effect of Vitamin D Levels on Intrapartum Epidural Consumption Oct 2014 presentation
    12 mg of Epidural for average vitamin D = 41 ng,
    18 mg of Epidural for average vitamin D = 26 ng
    Much less pain amoung the 93 women who had high levels of vitamin D.
    Note that scheduled cesareans were excluded from the analysis

Short url = http://is.gd/dpregnancy



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List of attached files
ID Name desc uploaded Size Downloads Actions
3437 pdf Preterm birth 10 percent WHO 2009.pdf PDF 23 Dec, 2013 by admin 439.61 Kb 248 View Download  
2994 pdf 70,000 IU.pdf 13 Sep., 2013 by admin 479.99 Kb 315 View Download  
264 gif Vitamin D preconception to birth - 2010.gif 2010 26 Oct., 2010 by admin 9.17 Kb 3095 View Download  
194 gif Knox on breastfeeding - 2010.gif Knox 27 Sep., 2010 by admin 18.51 Kb 3298 View Download  
193 gif Gum pockets vs vitamin D Hollis slides 2010 - 28.gif dental 26 Sep., 2010 by admin 15.53 Kb 3132 View Download  
192 gif Finland vitamin D for infants - Wagner 2010 pg 31.gif Finland 26 Sep., 2010 by admin 11.25 Kb 6601 View Download  
191 gif 6400 vs 400 IU during pregnancy - Wagner April 2010 pg 84.gif 6400 IU 26 Sep., 2010 by admin 12.28 Kb 7232 View Download  
190 gif 2000 and 4000 IU during pregnancy - Wagner April 2010 pg 51.gif 4000 IU 26 Sep., 2010 by admin 25.84 Kb 1003 View Download  
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Health Problems and D

  # of studies as of 11/02/14