Loading...
 

Criteria to associate a health problem with low vitamin D

A large number of health probems are associated with low vitamin D - see left column or chart below

If a yet another health problem has more than 7 of the following factors
then I believe that vitamin D deficiency might be a cause

  1. It has increased significantly recently ( 2X in a decade on average)
  2. Health problem increase has occured around the world
  3. Occurs more often when Far from Equator - but this factor has been decreasing during the past 20-30 years
    people can stay indoors, thanks to air conditioning
  4. Season - problem is worse in Spring when the vitamin D in the blood is the lowest
    Can now also happen in the Summer in the tropics if you can afford the air conditioning to stay away from the hot sun.
  5. Overweight - fat ties up a lot of vitamin D and the obese often do not feel comfortable out of doors
  6. Smoking - ties up vitamin D
  7. Medical problems which reduce vitamin D - MS, kidney, gut, liver, kidney, Bariatric Surgery, Cancer,..
  8. Dark skin - who get about 1/4 the amount of vitamin D per minute in the sun as those with light skin
  9. Seniors - who also get about 1/4 of the vitamin D per minute similar to those with dark skins - for a different reason
  10. Higher risk of the health problem if in another category for being at high-risk of being vitamin D deficient (besides overweight, senior, smoking, dark skin, shut-in)
       such as shut-in, pregnancy, excessive clothing, red-hair,
  11. Atmospheric haze - which reduces the UVB getting to the people - typically in cities
  12. Problem gets worse when taking a drug which reduces vitamin D
  13. A Patent has been issued for Vitamin D to treat or prevent the health problem
    such as: Breast and many other cancers, Obesity, Bone loss, Prostate, Fall prevention, stroke and other Cardiovascular, Immune system, heal wounds and reduce scars, Kidney disease, Diabetes, improve fertility, decrease pregnancy problems, (SAD), multiple sclerosis, chemoprevention of cancer, accelerate fracture healing, metabolic syndrome, periodontitis, gingivitis, endometreosis, hair loss, asthma, allergy, etc.
  14. The health problem is strongly associated with a vitamin D related disease
  15. Worse around the age of weaning from formula which had been fortified with vitamin D
  16. Is more common in rich families – who are more likely to apply sun screen,stay indoors, and want lighter skin
  17. Health problem is REDUCED by Ultraviolet light - from sun or UVB bulbs
  18. More in urban areas – less UVB in urban environments
  19. Less at high altitude - where there is more UVB ( Hypothesis: Colorado has the best UV (and thus best health) in the US )
  20. Less if person works outdoors 8X more likely to die if work indoors (1915)
  21. Worse in areas with increased clouds and rain - keeping people indoors, also, there is less UVB when outdoors
  22. Worse if born less than 12 months after previous sibling or as a twin - both of which reduces infant vitamin D levels

The following chart shows the current associations

Image

Possible interactions and vicious circles

Image


 Hill's Criteria to associate a health problem with something like vitamin D

CriterionDefining Question
Strength of the associationIs there a large difference in the outcome between exposed and non-exposed persons?
Consistency of the observed associationHas the outcome been observed by multiple researchers,
in various circumstances, places and at different times?
Specificity of the associationAre there specific persons or geographic locations associated with specific outcomes?
Temporality (temporal relationship of the association)Does the cause always precede the effect?
Biological gradientIs there a dose-response curve?
Plausibility of the biologyIs the suspected causation consistent with current knowledge of biology?
CoherenceAre there any serious conflicts with the biology or natural history of the disease?
Experiment (experimental
or quasi-experimental evidence)
Has an observed association led to a preventive action that has prevented the outcome?
AnalogyIs there an analogous exposure and outcome?


See also VitaminDWiki



See any problem with this page? Report it to the webmaster.

Health Problems and D

  # of studies as of 11/24/14