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Overview Loading of vitamin D

If a person is very deficient a loading dose should be considered

  • Loading dose would allow restocking the vitamin D in less than a month instead of 3-4 months
    • Alternate name = Stoss Treatment
  • Many doctors advise loading doses for those who are very vitamin D deficient (< 10 ng or < 20 ng)
  • Unfortunately
  1. Most doctors are only able to prescribe Vitamin D2, and not the far more effective Vitamin D3 - which you can get without a prescription
  2. Most doctors just give a large amount (usually D2) and wait a week to see if you get any bad reaction
    Far better is to start with a small amount of D3, say 2,000 IU and see if you are one of the 1 in 300 people who have a reaction to any type of Vitamin D
    If you get no reaction, then proceed with a loading dose (By the way, many of the reactions are due to a lack of Magnesium in the body)

Cholecalciferol loading dose guideline for vitamin D-deficient adults.

Eur J Endocrinol. 2010 Apr;162(4):805-11. Epub 2010 Feb 5.

CONCLUSION: The cholecalciferol loading dose required to reach the serum 25-OHD(3) target level of 75 nmol/l can be calculated as follows:
dose (IU)=40x(75-serum 25-OHD(3))xbody weight.
CLICK HERE for PDF of the study and equation
Equation into ng and pounds
   30ng (in ng and pounds) = 35 x (30-serum 25-OHD(3)) x body weight.
Typically spread over over 8 weeks
A very commonly prescribed loading dose in the US is 50,000 IU per week for 8 weeks, for a total of 400,000 IU
Example uses of the equation

140,000 IU 10 ng 200 lb
70,000 IU 20 ng 200 lb
105,000 IU 10 ng 150 lb

Chart shows a lot of variation from the equation = the solid line
Image


Fastest response time for a loading dose


See also at VitaminDWiki

See also web


Page last modified on 29 November, 2013


List of attached files
ID Name desc uploaded Size Downloads Actions
311 gif Loading dose guideline - April 2010.gif 26 Nov., 2010 by admin 16.14 Kb 8994 View Download  

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Health Problems and D

{#s as of April 10, 2014}