Many articles on this page
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From BetterBones.com Feb 2010
The story of the vitamin D–influenza link is actually telling the tale of the work done by Dr. John Cannell.
I have been in personal communication with Dr. Cannell over a number of years and have carefully followed his work and that of his non-profit Vitamin D Council.
When I first spoke with Dr. Cannell several years ago, he told me about his work as a psychiatrist at the Atascadero State Hospital in California.
Interested in vitamin D, and suspecting common vitamin D deficiency among his inmates, Dr. Cannell regularly tested inmates for vitamin D adequacy.
As he expected, he found they had abnormally low levels of vitamin D and, after explaining the benefits of this vitamin, he prescribed for the inmates 2000 IU vitamin D3 (cholecalciferol) a day.
In the late winter of 2005, a virulent strain of influenza hit the maximum-security psychiatric hospital, and although 10% of the 1200 patients ultimately developed the flu’s fever and debilitating muscle aches, there were, no cases of flu among Dr. Cannell’s inmates Dr. Cannell’s, who had been given daily vitamin D supplements. In a 2006 interview, Dr. Cannell said, “First, the ward below mine was quarantined, then the wards on my right, left, and across the hall.” And even though Cannell’s inmates had mingled with the others prior to quarantine, they still managed to avoid the flu.
How was it that his inmates were able to dodge the flu? A few months later, he came across a scientific report stating that vitamin D was found to increase the production of natural antimicrobial compounds in white blood cells. It was then that Dr. Cannell’s “Aha!” moment occurred. Could it have been the vitamin D he routinely gave his inmates that protected them from the flu? Encouraged by his colleagues, Dr. Cannell and seven other noted vitamin D scholars reviewed more than 100 articles that — in one way or another — linked vitamin D with enhanced immunity and fewer respiratory infections.
The research reports that pointed to a D–influenza link included findings like these:
- Many studies noted an association between rickets, the classic childhood disease of vitamin D deficiency, and increased respiratory infections.
- A research comparison of 80 rickets-free children found that children with very low 25(OH)D levels (less than 10 ng/mL) were 11 times more likely to be infected with respiratory infections than children with higher vitamin D levels.
- A 1994 study showed that intervention with vitamin D (60,000 IU a week) and calcium (650 mg/day) produced a significant reduction in the incidence of infections in children with subclinical rickets.
These early research findings, along with his own experience with his inmates, led Dr. Cannell to boldly suggest that vitamin D deficiency could underlie a vulnerability to influenza infection. Since the first article on influenza and vitamin D was published in 2006, a new body of research has developed that strongly supports the hypothesis that low vitamin D levels increase vulnerability to flu and that high vitamin D levels offer a protective effect.
In 2007, Dr. Cannell and colleagues published a second paper on the vitamin D–influenza connection in the Virology Journal. Here they explored 9 key questions including, “Why is influenza both seasonal and ubiquitous, and what happens to the virus between epidemics?” “Why are influenza epidemics so explosive?” “Why do they end so abruptly?” and so forth. An important part of the answers to each of these questions pertains to the fascinating role vitamin D plays in the enhancement of innate immunity.
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clipped from Physorg Dec 2010
WHO: "The average incidence of TB in prisons was 23 times higher that of the general population, and for latent TB, was 26 times higher in prisons than in the general population."
Note: Prisoners tend to get very little sunshine
Clipped from web Suicide rate 9X higher for females in prison that outside
Study Reveals Rising Suicide Rate In Female Prisoners 02 Feb 2009
Suicide is 20 times more common in female prisoners than in the general female population, according to new research. The research, published in the February issue of the British Journal of Psychiatry, also shows that the suicide rate for female prisoners has steadily increased over the last 25 years. And younger prisoners are at greater risk of killing themselves than older inmates. Psychiatrists Dr Seena Fazel, from the University of Oxford, and Dr Ram Benning, from Derby City Hospital, studied suicides in female prisoners between 1978 and 2004. Eight-three suicides were recorded in total.
The suicide rate for all female prisoners compared with the general female population of similar ages (also known as the standardised mortality ratio or SMR) was 20.7. In other words, female prisoners of all ages were about 20 times more likely to kill themselves than other women. This trend has been steadily increasing over the last 25 years.
When the researchers examined the suicide rates by age group, they found that suicide was far more common in younger inmates than older ones. Female prisoners under the age of 25 had an SMR for suicide of 40, compared with 20 for prisoners over the age of 25. This suggests that younger female prisoners are a particularly high-risk group for suicide.
In 2005, Dr Fazel and colleagues examined the suicide rate in male prisoners, and found that suicide was five times more common in male prisoners than in the general population. This new study therefore points to a clear 'gender gap' in suicide for male and female prisoners.
Dr Fazel and Benning put forward a number of explanations for this gender gap. For example, women entering prison may already be at a higher risk of suicide because they have existing mental health problems, such as depression, a history of self-harm, or a drug or alcohol addiction. The prison environment may also affect women differently to men.
Writing in the February issue of the British Journal of Psychiatry, they said: "One possible explanation for higher SMR for suicide in female prisoners is that females entering prison may have higher prevalences of risk factors associated with suicide, such as depression, previous self-harm and history of physical and sexual abuse. Substance misuse is a risk factor for prison suicides, and a systematic review has shown that the relative excess misuse in prisoners compared with the general population is higher for female inmates. Another explanation is that prison may specifically increase the vulnerability of females to suicide."
The researchers say the reasons for the increasing suicide rate in female prisoners over the last 25 years are 'complex'. However, a likely explanation is that more women are now being convicted for drug-related offences, meaning greater numbers of women are entering prison with drug problems.
The researchers say their latest findings support the need for national initiatives to help prevent suicide in prisoners.
"Suicides in female prisoners in England and Wales, 1978-2004"
Fazel S and Benning R (2009) British Journal of Psychiatry, 194: 183-184
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Update Feb 2012
Life, With Dementia New York Times
- In just 15 years 4X increase in number of US prisoners over age 55 (1995 to 2010)
- Experts believe that Alzheimer’s disease in prisons will grow 4X to 6X by 2040 (vs. 2X for all Americans)
Got to wondering about others (not just prisoners) who are kept away from the sun
Poor health due to lack of vitamin D: dementia, shorten life, etc. etc.
Senior homes, Assisted living
Submarines Vitamin D Supplementation in Underway Submariners
Long-haul truck drivers - 16 years reduced life expectancy
Shift workers (some)
Psychiatric hospitals - which is where Dr. Cannell first got interested in vitamin D
Increased Infectious Disease
- Sexually Transmitted Diseases
Increased Chronic Disease
- Heart Disease
- High Blood Pressure
Virtually all of the above Infectious and Chronic diseases are also associated with low vitamin D
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See also from VitaminDWiki
- Overview TB and Vitamin D
- All items in Immunity and vitamin D 109 items
- Overview Influenza and Vitamin D
- All items in category Winter blues and depression 91 items
- Overview Deficiency and Vitamin D
- Moscow prison to install tanning beds - Nov 2010
- Use of tanning beds would reduce associated deaths by 10X – Oct 2011
- All items in UV and Vitamin D 233 items
- Perhaps UV is Addicting
- All items Noontime Sun and Tanning and Vitamin D: 192 items
- Sun increases but tanning bed decreases longevity - April 2011.pdf file
- UV every two weeks maintains summer vitamin D level – RCT Oct 2011 extensive comments/observations by VitaminDWiki
- Overview Cognition and vitamin D
- Prisoners in psychiatric wards are very low on vitamin D – Oct 2012
- Prison doctor on lack of vitamin D in solitary confinement – July 2013
- Search VitaminDWiki for PRISON 97 items as of March 2014
- All items in category Shut-in and Vitamin D 17 items
- Suicidal patients are vitamin D deficient– Dec 2014