Fact: A properly functioning liver is needed for the efficient activation of vitamin D in the body
Fact: Liver diseases often result in lower levels of vitamin D
Fact: Various pain relievers damage the liver function
Fact: Lower levels of vitamin D result in osteoporosis and many other diseases
Options with a poorly functioning liver appear to be:
- Increased vitamin D (example: 2X more vitamin D if Liver is 1/2 as efficient)
- Increase the response you get from vitamin D
- Increase sunshine / UVB,
- Get the response you get from the sun/UVB
- Consider supplementing with Iron - a patented Iron supplement appears to work very well
- Get prescription for active form of vitamin D (Calcitriol) which does not need the liver to get the benefits of vitamin D in the body
- Get Calcidiol which also does not need the liver
See also VitaminDWiki
- All Liver items and Vitamin D 46 items
- Hepatitis C, non-alcoholic fatty liver disease and vitamin D deficiency – Dec 2014 great summary tables
- Important interactions between the liver and vitamin D – May 2013 excellent, with lots of graphs and tables
- Advanced liver cirrhosis death 6.3X more likely if extremely low vitamin D – Jan 2013
- Vitamin C reduces liver inflammation, which improves vitamin D production – Dec 2014
- The worse the chronic liver disease, the lower the vitamin D level – Review Dec 2012
- Death due to liver problems was 4X more probable with low levels of vitamin D – May 2012
- Liver injury associated with low level of vitamin D – April 2011
- Alcoholics with low vitamin D get more bone fractures – Jan 2011
- Magnesium and vitamin D Alcohol uses up Magnesium, which is needed for bone strength
- Vitamin D intervention stopped bone loss in mice getting too much alcohol – Aug 2012
- Pharmacology of vitamin D - April 2011 many details on Calcidiol by Glossman
- Vitamin D Deficiency and Liver Disease – Aug 2010 Question and Answer format
- Calcidiol , which does not require hydroxylation by the liver can be taken in place of vitamin D
- Vitamin D3 becomes Calcidiol which becomes Calcitriol
- Calcidiol may be 5X more effective than Vitamin D3 – June 2012
- Search VitaminDWiki for Calcidiol 462 items Nov 2012
- Active form of vitamin D (Calcitriol) cut in half the fractures following organ transplant – meta-analysis Aug 2011
- Calcitriol is available by prescription only
- Google Site search for Calcitriol 870 hits as of Nov 2012
- Oral vitamin D replacement is effective in chronic liver disease. – Aug 2010
- Just give more vitamin D if the liver is still somewhat functioning
- Overview Loading dose for vitamin D some people like to refill vitamin D levels quickly
- Loading doses should be appropriate for those with liver problems
- 25-Hydroxyvitamin D3 suppresses hepatitis C virus production – Oct 2012
- Hepatitis-C treatment greatly enhanced with 2000 IU of Vitamin D – RCT Dec 2011
- Graphs of diseases vs vitamin D levels - April 2011 has the following
Inflammatory diseases: review of vitamin D, with many tables – May 2014 which has a summary table
Most of the people with the diseases have less than 20 ng of vitamin D
See also Web
- PubMed alcohol "vitamin d" Nov 2012 258 items – examples follow
Role of obesity , alcohol and smoking on bone health 2012
Association of 25-hydroxyvitamin D levels with liver dysfunction and mortality in chronic liver disease – 2012
die more quickly if so much alcohol then liver dysfunction and low vitamin D
Assessing bone status in patients awaiting liver transplantation – 2011 88% had low vitamin D levels
What People Recovering from Alcoholism Need to Know About Osteoporosis NIH
- Acetaminophen is involved in the most common cause of acute liver failure in adults Nov 2011 full text on-line
- High Risk Groups for Poor Vitamin Status includes Alcohol
- Alcohol and Other Factors Affecting Osteoporosis Risk in Women with bone photos - from 2003
- Vitamin D Council - Anemia
- Vitamin D Council - Chronic Liver Disease
- The liver also processes Vitamin K
- EHow:Vitamin D & Liver Function
- Vitamin D is not considered an essential vitamin for liver function, but liver function is essential to providing vitamin D to the body.
- Hepatocellular carcinoma and vitamin D: a review = Liver Cancer, Nov 2011
- VITAMIN D & LIVER CANCER Live Strong Aug 2011
- Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease. April 2013
- Vitamin D deficiency in chronic liver disease Dec 2014
"Published studies provide evidence for routine screening for hypovitaminosis D in patients with liver disease"
Vitamin D levels may explain the racial differences in response rates to antiviral therapy for chronic hepatitis C.
Hepatology. 2011 Oct;54(4):1489. doi: 10.1002/hep.24447. Epub 2011 Jul 21.
Ji HF. No abstract; PMID: 21618570
Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.
J Hepatol. 2011 Oct;55(4):756-61. Epub 2011 Feb 18.
Terrier B, Carrat F, Geri G, Pol S, Piroth L, Halfon P, Poynard T, Souberbielle JC, Cacoub P.
Department of Internal Medicine, Université Pierre et Marie Curie, Paris, France.
Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C.
Transpl Int. 2011 Jan;24(1):43-50. doi: 10.1111/j.1432-2277.2010.01141.x.
Bitetto D, Fabris C, Fornasiere E, Pipan C, Fumolo E, Cussigh A, Bignulin S, Cmet S, Fontanini E, Falleti E, Martinella R, Pirisi M, Toniutto P.
Medical Liver Transplantation Unit, Internal Medicine, University of Udine, Udine, Italy.
Prevalence of vitamin D deficiency in chronic liver disease.
Dig Dis Sci. 2010 Sep;55(9):2624-8. Epub 2009 Dec 4.
Arteh J, Narra S, Nair S.
Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
CONCLUSION: Vitamin D deficiency is universal (92%) among patients with chronic liver disease, and at least one-third of them suffer from severe vitamin D deficiency.
African American females are at highest risk of vitamin D deficiency. PMID: 19960254
Heart transplant 19 ng vitamin D vs liver transplant 13 ng – April 2009 has the following graph