Overview Liver and vitamin D

Fact: A properly functioning liver is needed for the efficient activation of vitamin D in the body
Fact: Liver diseases often result in lower levels of vitamin D
Fact: Various pain relievers damage the liver function
Fact: Lower levels of vitamin D result in osteoporosis and many other diseases
Options with a poorly functioning liver appear to be:

  1. Increased vitamin D (example: 2X more vitamin D if Liver is 1/2 as efficient)
  2. Increase the response you get from vitamin D
  3. Increase sunshine / UVB,
  4. Get the response you get from the sun/UVB
  5. Consider supplementing with Iron - a patented Iron supplement appears to work very well
  6. Get prescription for active form of vitamin D (Calcitriol) which does not need the liver to get the benefits of vitamin D in the body
  7. Get Calcidiol which also does not need the liver

see wiki page http://www.vitamindwiki.com/tiki-index.php?page_id=949

See also VitaminDWiki

Image Image

Inflammatory diseases: review of vitamin D, with many tables – May 2014 which has a summary table
Most of the people with the diseases have less than 20 ng of vitamin D

Click on image for ways of getting vitamin D even if Liver is not functioning well

See also Web

Vitamin D levels may explain the racial differences in response rates to antiviral therapy for chronic hepatitis C.

Hepatology. 2011 Oct;54(4):1489. doi: 10.1002/hep.24447. Epub 2011 Jul 21.
Ji HF. No abstract; PMID: 21618570

Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis.

J Hepatol. 2011 Oct;55(4):756-61. Epub 2011 Feb 18.
Terrier B, Carrat F, Geri G, Pol S, Piroth L, Halfon P, Poynard T, Souberbielle JC, Cacoub P.
Department of Internal Medicine, Université Pierre et Marie Curie, Paris, France.

Vitamin D supplementation improves response to antiviral treatment for recurrent hepatitis C.

Transpl Int. 2011 Jan;24(1):43-50. doi: 10.1111/j.1432-2277.2010.01141.x.
Bitetto D, Fabris C, Fornasiere E, Pipan C, Fumolo E, Cussigh A, Bignulin S, Cmet S, Fontanini E, Falleti E, Martinella R, Pirisi M, Toniutto P.
Medical Liver Transplantation Unit, Internal Medicine, University of Udine, Udine, Italy.

Prevalence of vitamin D deficiency in chronic liver disease.

Dig Dis Sci. 2010 Sep;55(9):2624-8. Epub 2009 Dec 4.
Arteh J, Narra S, Nair S.
Department of Internal Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
CONCLUSION: Vitamin D deficiency is universal (92%) among patients with chronic liver disease, and at least one-third of them suffer from severe vitamin D deficiency.
African American females are at highest risk of vitamin D deficiency. PMID: 19960254

Heart transplant 19 ng vitamin D vs liver transplant 13 ng – April 2009 has the following graph


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