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Gout and Vitamin D

Many reasons to suspect Gout is associated with low vitamin D

  1. Gout is seasonal
    Acute gouty arthritis is seasonal. 1998 The most prevalent season is Spring 32% (when vitamin D levels are the lowest)
  2. Clinical Trials for Gout and Vitamin D
    Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function
    Good: 50,000 IU weekly, unfortunately: D2, not D3
  3. Vitamin D reduces Rheumatoid arthritis
  4. Vitamin D reduces pain
  5. Vitamin D reduces Inflammation category listing with 37 items
  6. Higher incidence of gout with age (less vitamin D as you get older)
  7. Increased gout at higher Latitude (Gout and Goutiness a 1899 book
  8. Increased gout with soda pop
    JAMA study from 2010.2 women >2 cans of soda daily 2X more likely to develop gout (Note that soda decreases vitamin D levels)
  9. 2X more Gout if Dark Skin
    WikiPedia gout is twice as likely in African American males as it is in European Americans
  10. Gout and Calcium and vitamin D
    Calcium and Vitamin D. The relationship of gout to calcium and vitamin D is complex.
    Gout is associated with insulin resistance, low vitamin D levels, and inflammation, all of which interfere with muscle synthesis.
    One study has found that patients with gout have lower vitamin D3 levels correlated with higher urate.
  11. Increased gout recently (along with increased numbe of people being vitamin D deficient)- both blacks and whites New Zealand 2009 publication

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See also VitaminDWiki

A large number of health probems are associated with low vitamin D - see left column or chart below

If a yet another health problem has more than 7 of the following factors
then I believe that vitamin D deficiency might be a cause

  1. It has increased significantly recently ( 2X in a decade on average)
  2. Health problem increase has occured around the world
  3. Occurs more often when Far from Equator - but this factor has been decreasing during the past 20-30 years
    people can stay indoors, thanks to air conditioning
  4. Season - problem is worse in Spring when the vitamin D in the blood is the lowest
    Can now also happen in the Summer in the tropics if you can afford the air conditioning to stay away from the hot sun.
  5. Overweight - fat ties up a lot of vitamin D and the obese often do not feel comfortable out of doors
  6. Smoking - ties up vitamin D
  7. Medical problems which reduce vitamin D - MS, kidney, gut, liver, kidney, Bariatric Surgery, Cancer,..
  8. Dark skin - who get about 1/4 the amount of vitamin D per minute in the sun as those with light skin
  9. Seniors - who also get about 1/4 of the vitamin D per minute similar to those with dark skins - for a different reason
  10. Higher risk of the health problem if in another category for being at high-risk of being vitamin D deficient (besides overweight, senior, smoking, dark skin, shut-in)
       such as shut-in, pregnancy, excessive clothing, red-hair,
  11. Atmospheric haze - which reduces the UVB getting to the people - typically in cities
  12. Problem gets worse when taking a drug which reduces vitamin D
  13. A Patent has been issued for Vitamin D to treat or prevent the health problem
    such as: Breast and many other cancers, Obesity, Bone loss, Prostate, Fall prevention, stroke and other Cardiovascular, Immune system, heal wounds and reduce scars, Kidney disease, Diabetes, improve fertility, decrease pregnancy problems, (SAD), multiple sclerosis, chemoprevention of cancer, accelerate fracture healing, metabolic syndrome, periodontitis, gingivitis, endometreosis, hair loss, asthma, allergy, etc.
  14. The health problem is strongly associated with a vitamin D related disease
  15. Worse around the age of weaning from formula which had been fortified with vitamin D
  16. Is more common in rich families – who are more likely to apply sun screen,stay indoors, and want lighter skin
  17. Health problem is REDUCED by Ultraviolet light - from sun or UVB bulbs
  18. More in urban areas – less UVB in urban environments
  19. Less at high altitude - where there is more UVB ( Hypothesis: Colorado has the best UV (and thus best health) in the US )
  20. Less if person works outdoors 8X more likely to die if work indoors (1915)
  21. Worse in areas with increased clouds and rain - keeping people indoors, also, there is less UVB when outdoors
  22. Worse if born less than 12 months after previous sibling or as a twin - both of which reduces infant vitamin D levels

Many reasons why vitamin D deficiency has become epidemic which includes the following chart
For more information, see wiki page http://www.vitamindwiki.com/tiki-index.php?page_id=1586

See also web

See also web - treatments

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Page last modified on 08 April, 2014


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Health Problems and D

  # of studies as of 7/21/14